G7 leaders agree Nature Compact

G7 leaders have agreed commitments to halt and reverse biodiversity loss by 2030, and tackle deforestation, marine litter and illegal wildlife trade

G7 leaders have agreed commitments to halt and reverse biodiversity loss by 2030, and tackle deforestation, marine litter and illegal wildlife trade.

At the G7 Leaders’ Summit in Cornwall yesterday, countries came together and agreed a shared G7 Nature Compact.

This is a key agreement which brings G7 countries together to address the most pressing international and interlinked challenges of biodiversity loss and climate change. Leaders have also agreed to review progress against the Nature Compact to ensure delivery of its 2030 vision.

This next milestone marks a crucial commitment to supporting global consensus and taking bold action for the delivery of ambitious outcomes for nature in 2021. Climate change is one key driver of biodiversity loss, and protecting, conserving and restoring biodiversity is crucial to addressing climate change.

The G7 Nature Compact commits world leaders to:

  • Shift incentives and use all appropriate levers to address unsustainable and illegal activities negatively impacting nature, such as through tackling deforestation by supporting sustainable supply chains, and stepping up efforts to tackle the illegal wildlife trade
  • Work to dramatically increase investment in nature from all sources, and to ensure nature is accounted for in economic and financial decision-making – for instance, through drawing on the Dasgupta Review for key actions
  • Support and drive the protection, conservation and restoration of ecosystems critical to halt and reverse biodiversity loss and tackle climate change, such as supporting the target to conserve or protect at least 30% of global land and at least 30% of the global ocean by the end of the decade
  • Hold themselves to account for taking domestic and global action for nature through driving strengthened accountability and implementation mechanisms of all Multilateral Environmental Agreements to which we are parties

Through this Compact, the UK Government is committing to supporting the global consensus and to taking bold action for delivery of ambitious outcomes for nature in 2021 at the Convention on Biological Diversity (CBD) COP15 in Kunming and United Nations Framework Convention on Climate Change (UNFCCC) COP26 in Glasgow.

The Prime Minister has also launched the UK’s Blue Planet Fund. The £500 million fund will support countries to tackle unsustainable fishing, protect and restore coastal ecosystems like mangroves and coral reefs, and reduce marine pollution.

Environment Secretary George Eustice said: “For the first time, the G7 has committed to halting and reversing the loss of biodiversity in the next decade.

“This is a major step forward on the path to CBD COP15 and COP26 and is a sign of the dedication to accelerate action within the G7 – and beyond – to tackle the interdependent crises of climate change and biodiversity loss.

“We have seen major progress this weekend and we welcome the collaboration between global leaders to raise our ambition and remain accountable in this critical decade.”

The Compact’s commitments will be embedded in national plans as appropriate, raising ambition wherever possible, and the G7 will hold themselves to account for delivering effective action integrated with that to support climate change mitigation and adaptation.

Through existing G7 mechanisms, including at the G7 Leaders’ Summit in five years, the G7 countries will review options to ratchet up action and ambition, as needed, to ensure delivery of the vision for 2030.

The full G7 Nature Compact can be read online here.

Your sight could be lost if you don’t attend eye-screenings, charity warns diabetics

As the covid crisis hopefully eases, concerns are being focused on the impact of lockdown on other health conditions. With health centres forced to postpone routine screenings last year, there are fears some conditions may have worsened in the absence of early diagnosis and treatment.

During Diabetes Week this week [June 14-20th], the national sight loss charity RNIB Scotland is emphasising it is more important than ever that people with diabetes attend their regular check-up appointments, now that these have resumed.

RNIB director James Adams said: “Diabetic retinopathy, a complication of diabetes, can affect the small blood vessels at the back of the eye and is a major cause of sight loss among working-age adults. But damage to vision can be arrested if detected early enough.

“While it’s possible that diabetes won’t cause any changes to your sight, the most effective thing you can do to prevent this is to go to your retinal screening appointments and eye examinations, where safety measures are in place.”

The message is also being emphasised by NHS Scotland. Dr Mike Gavin, clinical lead for the national Scottish Diabetic Eye Screening Programme said: “We are working hard to see patients for screening, after the service was temporarily paused during the first lockdown in 2020. Patients should always attend screening whenever they are invited to prevent avoidable loss of sight.”

Each year, 5,500 patients with diabetes in Scotland need to undergo further imaging or see an NHS eye specialist for the first time due to worsening in their retinopathy.

There are 3.5 million people in the UK who have been diagnosed diabetes, and an estimated 500,000 people living with undiagnosed diabetes. Within 20 years of diagnosis, nearly all people with type 1 diabetes and almost two-thirds of people with type 2 diabetes will have developed some form of diabetic retinopathy. People with diabetes are also at increased risk of glaucoma and cataracts.

People from a South Asian or African-Caribbean background are two to four times more likely to get type 2 diabetes. They tend to develop it at a younger age which means they live with the condition for longer.

The risk of complications increases with the length of time people have the condition. It is not known why this is the case, but it is likely to be a mixture of genetics, lifestyle, and environmental factors.

RNIB Scotland is on the steering committee of a five-year study that is following 1,100 retinopathy patients from across Scotland.

The LENS (Lowering Events in Non-proliferative retinopathy in Scotland) trial is testing whether a cholesterol-lowering medicine, fenofibrate, can slow the progression of retinopathy.

LENS is being co-ordinated by the Universities of Oxford and Glasgow in partnership with Aberdeen, Dundee and Edinburgh, and with NHS Scotland’s Retinal Screening Service. More information about the trial is available at: www.ctsu.ox.ac.uk/lens.

* If you’re worried about your vision, contact RNIB’s Sight Loss Advice Service on 0303 123 9999 or visit www.rnib.org.uk/eyehealth

For more information on the NHS Scotland eye-screening service, visit  https://www.nhsinform.scot/illnesses-and-conditions/diabetes/diabetic-retinopathy.

Hope for Isabella

The parents of a six-week old baby girl who is one of the first in the UK to be given access to a new, potentially life-saving drug are thanking the NHS Greater Glasgow and Clyde team for giving their daughter a chance of a normal, healthy life.
 
Isabella Winfield was born on 30 April in Elgin to her parents Richard and Margaret, and within her first day of life it was clear that something was not quite as it should be.
 
Mum Margaret, from Archiestown said: “From her first check-up, the midwife was concerned that Isabella appeared to be floppy and told us she would need to refer her on to the paediatricians. From then they started lots of tests, focussing on her muscle function.
 
“As a new mum it was quite overwhelming. One minute I was a new mum, the next I had a very sick baby. But the team were great and their support was invaluable. Gene tests were started and we waited 11 days for the results.”
 
Tests concluded that Isabella had Spinal Muscular Atrophy. Babies born with Type 1 SMA, which is the most common form of the condition, experience progressive muscle weakness, loss of movement, difficulty breathing. Sadly, without treatment, 90% don’t survive past their first year of life.
 
While this was devastating news, there was hope – in the form of Zolgensma. Zolgensma has just been made available on the NHS after the health service struck a deal with manufacturers Novartis Gene Therapies.
 
Margaret said: “I was aware of Zolgensma but thought it was still in trials. As soon as they said it was available to us, we just thought yes, go for it. We had no hesitation. If it’s available for her, it’s her best hope.”

Looking after Isabella and her family was Royal Hospital for Children neurologist Dr Iain Horrocks, who has spent his career specialising in neuromuscular disorders in children.


Dr. Horrocks said: “Tragically, most babies with Type 1 SMA would die within six months. There was no treatment. It’s a disorder of the Motor Unit and the missing gene means messages from the spinal cord where the gene is located to the muscles aren’t received. This results in muscle atrophy (or death). Typically it presents as babies struggled to feed, but it was often as late as six months before it became apparent.
 
“For the last few years we have had access to a drug which works well in stopping muscle deterioration, but it needs to be given every four months for life. It’s injected into the spine. As they get older, patients hate getting it and there can be problems getting access to the spine, so it’s not ideal. And it’s not a gene therapy.
 
“Zolgensma is a game changer. Time is of the essence – the sooner it’s given the better and muscle function is protected from any further deterioration. Literally every day counts. It’s also less invasive as it’s given as a single, once only infusion, rather than being injected into the spine.”
 
Isabella was diagnosed at just 11 days old and nine days later received her potentially life-saving treatment.
 
He said: “It all happened really quickly. I met them on the Wednesday with the diagnosis “virtually” with my colleague Dr Elma Stephen from Aberdeen Children’s Hospital. We brought them down to the Royal Hospital for Children in Glasgow, the following Wednesday, gave her some steroids, and infused her on the Thursday.
 
“Isabella was the ideal candidate for Zolgensma. As she presented so young she managed the viral load of the gene therapy infusion really well. She was the perfect candidate for this treatment presenting at the perfect age”.
 
“I’m so pleased that we got to her so early. We only treated her about three weeks ago when she was only three weeks old, so it is probably too early to talk about the future, but we are, of course, optimistic. She is prime candidate to do really well with this therapy and we should see some real improvements with her in the next couple of months.
 
“The expectation from Isabella is that she could go on to hit her motor milestones within the WHO (World Health Organisation) classifications, such as sitting, standing and walking. So we really hope she will progress nicely, albeit, she will be a bit weak. We hope she will be able to have a full life whereas a few years ago I would never have been able to talk about SMA babies like this.”
 
Dr Horrocks says he feels re-invigorated in his work, having had so many years where he was unable to hold out any hope for babies like this and their families.
 
He added: “This has radically turned the approach with these patients on its head! It re-enthuses you for your work. I think I can do this for the next 15 or 20 years because it makes it all worthwhile. I am very hopeful for children with this condition in the coming years. It’s life changing.”
 
Back in Archiestown, Richard, Margaret and baby Isabella are settling into life – with hope for her future.
 
Margaret said: “At the end of the day, we have hope for her to go on and be a happy, healthy little girl. We are so grateful to everyone involved.”

Fan Zone: Test kits being mailed to fans as Covid numbers rise again

Rapid lateral flow test kits will mailed from today to all visitors to the Glasgow Fan Zone to encourage testing. 17,000 ticket holders due attend the UEFA EURO 2020 Fan Zone at Glasgow Green will be contacted.

The move is part of a series of measures to help reduce the risk of transmission before and after the event.

In addition, a mobile testing bus is also now at Glasgow Green to provide on-site lateral flow testing, while attendees may be asked by COVID marshals on site whether they have taken a test as part of ongoing reporting on the site.

Health Secretary Humza Yousaf confirmed the arrangements yesterday as he was given a tour of the facility alongside Scotland’s National Clinical Director Professor Jason Leitch.

Mr Yousaf said: “I am encouraged to see first-hand all the mitigations in place at the fan zone which have helped to ensure that it is a low risk event. Supporters can gather here safely in a controlled environment – with necessary physical distancing and hygiene measures in place – to enjoy the football.

“I am also pleased that feedback from fans and staff so far on the arrangements in place – and the atmosphere – has been overwhelmingly positive.

“Ticket holders have already been contacted to emphasise the importance of self-testing. It is important to test both before and after the event, so we are now offering test kits to all fans attending to help minimise the risk of transmission. Additionally a mobile testing unit will be on site. Anyone with symptoms of COVID-19 or whose receives a positive test result must stay away, self-isolate and book a PCR test.

“Stewards will closely monitor the site and ask a sample of attendees about uptake of testing prior to arriving, while public health advisors will continue to look at data to ensure the event is being managed as safely as possible.

“The fan zone provides a focal point for celebrations and showcases the city. We want other businesses in Glasgow, including bars and restaurants, to be able to benefit from a boost in trade as a result of the tournament.”

Earlier slots for over-40s to help combat Delta variant

In another development, people over 40 whose second coronavirus (COVID-19) vaccination appointment is scheduled more than eight weeks after their first are now being encouraged to seek an earlier slot.

It follows recent advice from the Joint Committee on Vaccination and Immunisation (JCVI) recommending that the interval for second doses be brought forward from 12 to eight weeks – where supply allows –  particularly in areas where the Delta variant is a major threat.

The national vaccination programme is already scheduling appointments to reflect the latest guidance. However, many people – particularly over 40s – have already received an invitation in line with the previous recommendation of a 12 week interval, and they are now being invited to reschedule an earlier appointment.

Supplies permitting this will also apply to under 40s when their second dose appointments are due.

A new vaccine journey tool on the NHS Inform website allows people to check the status of their second appointment. If it is more than eight weeks from the first, another slot can be booked if there is one available. The national helpline can also be used, and drop-in clinics are being set-up around the country.

Health Secretary Humza Yousaf said: “We are working closely with NHS boards to ensure the number of appointments can be increased in line with national guidance to help combat new variants and provide protection to as many people as possible.

“Boards are boosting their capacity to administer second doses alongside the delivery of first doses to younger cohorts and appointments are now being issued in accordance with the new recommendation of an eight week gap.

“The second dose is vital in providing greater and longer lasting protection against the virus – particularly the new Delta variant. In line with the advice from the JCVI, we encourage those whose appointment was already scheduled – which is mainly over 40s at this time – to use the NHS Inform online tool, drop-in clinics or the national helpline to get their second dose appointment as close to eight weeks after their first as possible.

“In the six months since vaccinations started in Scotland we have delivered first doses to more than three quarters of the adult population and second doses to more than half. We remain on track to offer the vaccine to all adults by the end of July, but the emergence of the new variant shows we cannot be complacent.

“The vaccination programme is one of the main ways – along with restrictions and testing – that we are working to beat this virus and so it is crucial that everyone attends for their appointments.”

LOCKDOWN easing in England is set to be delayed.

So-called ‘Freedom Day’ was scheduled for 21 June, but Prime Minister is likely to announce a four week delay to retrictions when he addresses the nation at a press conference this evening.