In a major report today Westminster’s Science, Innovation & Technology Committee calls for steps to develop the potential of bacteria-killing viruses – called bacteriophages or phages for short – that can provide an alternative to antibiotics that are attracting growing resistance.
Phages have been used as therapy for over a hundred years, but interest has increased in recent years as the widespread use of antibiotics is leading to alarming antimicrobial resistance (AMR) to even the most effective treatments. But they have never been licensed for therapeutic use in the UK. They have only been used as “compassionate” treatments of last resort in isolated cases of otherwise intractable infections.
One of the problems has been an impasse: in order to be deployed in clinical trials phages must be manufactured to the Good Manufacturing Practices (GMP) standard – but investment in compliant manufacturing plants will only be justified following successful clinical trials.
Rt Hon Greg Clark MP, Chair of the Committee, said: “Phages offer a possible response to the increasing worldwide concerns about antimicrobial resistance.
“But the development of phage therapies is at an impasse, in which clinical trials need new advanced manufacturing plants, but investment requires clinical trails to have demonstrated efficacy.
“The Committee is asking the Government to consider whether the mothballed Rosalind Franklin Laboratory in the West Midlands could provide a suitable facility.
“The Laboratory, which has already received over £1 billion of public funding, was established by the Government to bring to an end the inadequacy of testing capacity that so hampered the national response to Covid.
“It consists of modern, secure laboratory facilities and was meant to be an important source of national resilience against future pandemics. But the Rosalind Franklin Laboratory has suddenly appeared for sale on the property website Rightmove, to the astonishment of the science and health communities.
“Our Committee’s report on phages asks for the Rosalind Franklin Laboratory to be considered for this purpose, rather than be lost to the nation and to science in a firesale.”
The Committee recommends that the Government should consider establishing a small GMP facility on the lines of the Catapult network which provides shared facilities for companies who cannot afford to make the level of investment on their own.
The Committee also calls on the Medicines and Healthcare Products Regulatory Agency (MHRA), Department for Health and Social Care (DHSC), and phage researchers to work together to make for a more promising route for phage research to be funded and its products licensed for use.
The Committee calls for:
Awareness-raising for healthcare students and professionals of the antimicrobial potential of phages where antibiotics have failed or are failing
Government and its agencies to make a definitive and positive statement on the role of phages in the national approach to anti-microbial resistance (AMR), which is important in research funding decisions and for private investment in commercial phages
The MHRA to consider allowing the compassionate use of non-GMP phages produced in the UK for last resort medical cases where other medical approaches have failed or are failing
The MHRA to review how current regulations would govern liability for clinicians and hospitals who used UK non-GMP phages,
JUDGES have ruled that the UK Government’s block of Scottish gender legislation was LEGAL.
The Holyrood parliament passed legislation to make it easier for people to change their sex last year, but the UK Government blocked the law, arguing that Scotland’s gender law would impact on equality laws across all countries of the UK
The Scottish Government challenged Westminster’s action through the courts, but yesterday The Court of Session in Edinburgh upheld the UK Government’s decision.
The Scottish Government is studying the detail of the judgement and has yet to make an official statement, but First Minister said the Supreme Court judgement marks ‘a dark day for democracy’.
Scottish Secretary Alister Jack takes a different view, of course.
The Secretary of State for Scotland, Rt Hon Alister Jack MP said: “I welcome the Court’s judgment, which upholds my decision to prevent the Scottish Government’s gender recognition legislation from becoming law.
“I was clear that this legislation would have had adverse effects on the operation of the law as it applies to reserved matters, including on important Great Britain-wide equality protections.
“Following this latest Court defeat for the Scottish Government, their ministers need to stop wasting taxpayers’ money pursuing needless legal action and focus on the real issues which matter to people in Scotland – such as growing the economy and cutting waiting lists.”
The Scottish Government is unlikely to take Mr Jack’s advice and has 21 days to decide whether to lodge an appeal.
Victoria Atkins aims to make health and social care system faster, simpler and fairer for patients
Health and Social Care Secretary sets out intention to make the system faster, simpler and fairer for patients
Victoria Atkins thanks staff for a week of delivery, in which two manifesto commitments were met
Health and Social Care Secretary Victoria Atkins has thanked health, social care and research staff for delivering on patients’ priorities, as she set out her commitment to make the health and social care system faster, simpler and fairer for patients.
Her words came days after pharmacies across the country began offering new contraceptive services and additional blood pressure checks, and after a breakthrough in talks to end consultant strikes, which saw the British Medical Association Consultants committee agree to put an offer on contract reform to its members.
Health and Social Care Secretary, Victoria Atkins, said: “Since joining the department, I have been bowled over by the way health and social care staff just keep on delivering for patients. The important milestones we’ve reached this week – reaching 50,000 additional nurses and 50 million more GP appointments – demonstrate real progress.
“I have spent the past few weeks meeting doctors, nurses, GPs, pharmacists and other health workers and heard wonderful stories about how they have gone above and beyond to deliver outstanding care for patients and cut waiting lists.
“But I have also heard about their frustrations and where they feel they are not able to deliver the best possible care or where prevention or early intervention could have made a real difference. That is why I am committed to making health and social care services faster, simpler and fairer.
“We face a difficult winter ahead. And though our early winter planning is seeing some results we know there is much more to do. But having seen what our excellent staff can do I am confident that with the government’s support we can continue to deliver for patients over the coming months.”
The Health and Social Care Secretary has committed to making health and social care services:
Faster for patients, by making it easier to get treatment locally, improving A&E performance and cutting waiting lists
Simpler for patients, with joined up, integrated care, and simpler for staff, by reducing bureaucracy and giving them the latest technology to free up their time to care for patients
Fairer, ensuring children are protected from health harms, that health outcomes are not determined by where you live, that government supports older people to maintain their independence for longer, and that government delivers a more productive NHS that is fairer for taxpayers.
She added that she would continue to work with the NHS to manage the ongoing winter pressures. The government prepared for winter earlier than ever before and data released by the NHS on Thursday shows the government is making good progress.
Compared to the same time last year, ambulance handover delays have fallen by 28%, thousands more 111 calls are being answered within 60 seconds, and there were nearly 1,500 more hospital beds available.
The Secretary of State said: “We face a difficult winter ahead. And though our early winter planning is seeing some results we know there is much more to do.
“But having seen what our excellent staff can do I am confident that with the government’s support we can continue to deliver for patients over the coming months.”
The Health and Social Care Secretary was appointed on 13 November. She has now set out her priorities in a week in which the government and NHS hit a number of major delivery milestones:
NHS England data published on Thursday showed there were 51,245 additional nurses in September 2023 compared to 2019 – hitting the government’s manifesto commitment to recruit an additional 50,000 nurses six months early.
NHS England data also showed that for the year to October 2023, there were 51 million additional general practice appointments delivered when compared to October 2019, meeting another manifesto commitment.
On Monday the government announced that it had put forward an offer that will modernise the consultant contract and reform consultants’ pay structure, paving the way to end consultant strikes. The British Medical Association and Hospital Consultants and Specialists Association will put the deal to their memberships in the coming weeks.
On Wednesday the Secretary of State announced funding for a research project to evaluate the rollout of the hugely successful HIV opt-out testing programme to 46 new sites across England.
On Friday 1 December pharmacies across England began offering the new contraceptive services announced recently as part of Pharmacy First. This is part of the NHS and government’s Primary Care Recovery Plan, announced by the head of the NHS and the Prime Minister in May, which committed to making it quicker and easier for millions of people to access healthcare on their high street.
WESTMINSTER’s Scottish Affairs Committee has published the UK Government’s response to its report on Promoting Scotland Internationally, in which MPs found the UK and Scottish Governments often collaborate well when promoting Scotland’s interests abroad but more work is needed to highlight modern Scottish successes.
In its report, the Committee found a clear strategy was needed to ensure UK embassies have access to guidance and clear expectations for holding events on key Scottish dates such as St Andrew’s Day.
The cross-party group of MPs recommended embassy staff of all levels be trained up on the current Scottish industry landscape and the UK Government’s priorities for Scotland in order to ensure a more consistent base of knowledge.
They also found more needed to be done to celebrate contemporary Scottish successes in fields such as scientific research, space and energy in addition to the more traditional attributes of the Scottish brand which still resonate on the international stage.
In its response, the UK Government highlighted past events but didn’t commit to implementing a strategy for celebrating key dates in the Scottish calendar across all embassies.
The UK Government also indicated senior staff receive adequate training but did not commit to giving staff of all levels updated training on the Scottish market and industry landscape.
The UK Government indicated agreement with the Committee that officials from the UK and Scottish Governments regularly work collaboratively overseas in order to deliver the best possible outcomes, and also acknowledged the importance of maintaining regular communication between teams.
The UK Government failed, however, to address a number of the Committee’s recommendations, including no commitment to provide specific information on the UK Government’s current priorities and objectives for promoting Scotland internationally.
Scottish Affairs Committee Chair Pete Wishart MP said: “Scotland is home to a fantastic array of research and development organisations, businesses and academic institutions – so it’s critical that Scotland’s success stories are promoted in a consistent and coherent way on the world stage.
“As a Committee, we found there were differing levels of engagement and knowledge related to Scotland’s key interests around the globe as well as a lack of a clear idea of exactly what the UK Government’s priorities are for promoting Scotland internationally.
“As Scots worldwide celebrate St Andrew’s Day, I’m disappointed that the extent to which embassies around the globe are telling the nation’s story and celebrating Scottish culture will remain inconsistent.
“Unfortunately, it was hard to identify a clear plan which will ensure Scotland receives the international recognition it deserves. It is, therefore, difficult to see how the UK Government will fully support Scotland to maximise the potential offered by our brilliant industries.”
The Home Affairs Committee is inviting members of the public to take part in a survey to inform its inquiry into fraud.
The cross-party committee of MPs wants to find out more about the different types of fraud that people are experiencing in the UK. They also want to hear about the impact this has had and what support people have received.
Fraud is the most common form of crime in England and Wales, accounting for 40% of reported offences and costing UK households over £1 billion every year. It can take many forms including phishing scams, identity theft and romance fraud. Fraud increasing takes place using digital technologies and online platforms; and perpetrators can often be based outside the UK making detection and protection more difficult.
The quick-to-complete survey consists of multiple choice questions, with the option for people to provide more information if they would like to. Everyone is welcome to take part, but they should note that the Committee is unable to take action on individual cases.
Launching the survey, Dame Diana Johnson said: “Fraud is the most common form of crime in this country with over 3 million cases recorded every year, and probably millions more going unreported.
“But behind these figures are individual victims of all ages and backgrounds, many of whom will have suffered h long-lasting financial and emotional consequences.
“We have launched this survey to find out what types of fraud people experience in the UK. The information you give us will help us understand how well current fraud strategies are working.
“It will also help us to learn what gaps there may be in the support that victims of fraud receive, and to identify where improvements can be made.”
Where to get help
We understand that the issues raised in this work may be sensitive or upsetting. If you have been affected by any of the issues raised in this inquiry, you may wish to contact your GP, local MP or the following organisations:
Police Scotland – call 101
Reporting fraud and cyber crime | Action Fraud Call 0300 123 2040 Monday to Friday 8am – 8pm. Action Fraud will guide you through simple questions to identify what has happened and their advisors are available twenty four hours to give you help and advice if you need it.
FIRST MINISTER CALLS FOR RECOGNITION OF STATE OF PALESTINE
MSPs have voted in favour of an immediate ceasefire in Gaza and the immediate and unconditional release of all hostages held by Hamas, following a debate in the Scottish Parliament.
Opening the debate, First Minister Humza Yousaf said the chamber was unified in resolute condemnation of Hamas’ abhorrent terrorist attacks and the humanitarian catastrophe unfolding in Gaza.
This followed a letter sent by the First Minister to the Prime Minister and Sir Keir Starmer this morning, calling for the UK to officially recognise the State of Palestine in order to break the political impasse that has condemned Israelis and Palestinians to successive cycles of violence.
The First Minister said: “In Scotland, the Muslim and Jewish communities have enjoyed decades of friendship, decades of shared humanity and faith. Nowhere is that more evident than in East Renfrewshire, home of Scotland’s largest Jewish community, and a significant Muslim population too, who have lived side-by-side in harmony for many years.
“But we cannot be complacent. We must all be proactive in rooting out any hint of Islamophobia or antisemitism wherever it occurs. Presiding Officer, even though it feels impossible to look past the current horrors of war, we must ensure that this perpetual cycle of violence that we see occur far too often finally ends, once and for all, in a peaceful resolution.
“To that end, there must be a renewed, and serious international effort towards a two-state solution. Israeli and Palestinian states that can co-exist in safety, security and with equal rights for each of its citizens.
“Unfortunately, the world has not kept its promise to the Palestinian people. They have not been given a free sovereign state, along the 1967 borders, as they were promised. Quite the opposite.
“The continued expansion of Israeli settlements in the occupied West Bank is not only illegal but works against a peaceful resolution. So it is simply not enough anymore to pay lip-service to a two-state solution, we must take steps to turn that into a reality.
“To that end, I have written to the Prime Minister, and to Sir Keir Starmer, and urged them to immediately take steps to ensure the UK recognises the State of Palestine. It is only with full recognition of Palestine, as a State in its own right, that we can truly move forward towards a two-state solution.
“To conclude, Presiding Officer, to prevent further deaths, the bombs, the rockets – they must stop. The Scottish Government continues to call for an immediate ceasefire, for the safe release of all hostages, for an end to the killing of innocent civilians in Gaza, for an end to the siege of Gaza, and for all parties to abide by international law.
“The UK government and the international community must use their influence to prevent the further loss of innocent life. Every child the world over deserves to grow old. The children of Gaza and Israel deserve nothing less. It is our moral obligation to act. Let us hope even in these, the darkest of times, that humanity prevails.”
First Minister Humza Yousaf has written to Prime Minister Rishi Sunak calling for the United Kingdom to officially recognise the State of Palestine to break the political impasse that has condemned Israelis and the Palestinians to successive cycles of violence.
The FM’s appeal came on the day Scotland’s MSPs voted in favour of ceasefire in Palestine.
The letter, sent ahead of a debate on the situation in the Middle East in the Scottish Parliament yesterday, has also been sent to the Leader of the Opposition in the UK Parliament Sir Keir Starmer.
The First Minister later opened the Holyrood debate on a Government motion which condemned the Hamas atrocities on 7 October, called for the release of the hostages and for all parties to agree to an immediate ceasefire.
“But our message is clear: if you are fit, if you refuse to work, if you are taking taxpayers for a ride – we will take your benefits away.”
Changes are part of the new Back to Work Plan which will help up to 1,100,000 people with long-term health conditions, disabilities or long-term unemployed to look for and stay in work.
Additional support comes alongside tougher sanctions for people who don’t look for work, as part of the next generation of welfare reforms.
Includes exploring reforms of the fit note system, expansion of available treatment and employment support, and formal launch of the WorkWell service to help people start, stay and succeed in work.
The Chancellor Jeremy Hunt and the Secretary of State for Work and Pensions Mel Stride will unveil their Back to Work Plan– a package of employment focused support that will help people stay healthy, get off benefits and move into work – as part of the Autumn Statement.
Building on the ambitious £7 billion employment package from Spring Budget the Chancellor is using his Autumn Statement to outline a new Back to Work Plan, which will expand the employment support and treatment available and reform the ways that people with disabilities or health conditions interact with the state.
Getting more people into work and ensuring work pays remains a key priority for the government. It is important for growing the UK economy, managing inflation, controlling spending, and improving living standards. Getting more people into good jobs is also good for those individuals and the best route out of poverty.
The government is boosting four key programmes – NHS Talking Therapies, Individual Placement and Support, Restart and Universal Support – to benefit up to 1.1 million people over the next five years and help those with mental or physical health conditions stay in or find work.
The new WorkWell service as announced at Spring Budget and delivered by the Departments for Work and Pensions and Health and Social Care is also being formally launched today and will support almost 60,000 long-term sick or disabled people to start, stay and succeed in work once rolled out in approximately 15 areas across England.
The prospectus that will be launched in the coming weeks will provide information for all Integrated Care Systems across England to develop their localised work and health strategy.
Ministers are also planning to trial reforms to the fit note process to make it easier and quicker for people to get specialised work and health support, with improved triaging and signposting. Since the pandemic the number of people inactive in the UK due to long-term sickness or disability has risen by almost half a million to a record high of 2.6 million, with mental health, musculoskeletal conditions and heart disease being some of the main causes.
Stricter benefit sanctions will also be enforced by the Department for Work and Pensions for people who are able to work but refuse to engage with their Jobcentre or take on work offered to them. Benefit claimants who continue to refuse to engage with the Jobcentre will face having their claim closed. The latest published data shows that there were 300,000 people who had been unemployed for over a year in the three months to July.
The announcement today forms part of wider plans to grow the economy expected in the Autumn Statement on Wednesday 22 November. The Chancellor is set to reveal a raft of changes to get the UK economy growing including getting people back into work.
Chancellor of the Exchequer, Jeremy Hunt, said:“We’re serious about growing our economy and that means we must address the rise in people who aren’t looking for work – especially because we know so many of them want to and with almost a million vacancies in the jobs market the opportunities are there.
“These changes mean there’s help and support for everyone – but for those who refuse it, there are consequences too. Anyone choosing to coast on the hard work of taxpayers will lose their benefits.”
Secretary of State for Work and Pensions, Mel Stride, said:“We are rolling out the next generation of welfare reforms to help more people start, stay and succeed in work. We know the positive impact work can have, not just on our finances, but our health and wellbeing too.
“So we are expanding the voluntary support for people with health conditions and disabilities, including our flagship Universal Support programme.
“But our message is clear: if you are fit, if you refuse to work, if you are taking taxpayers for a ride – we will take your benefits away.”
The plans announced today set out how the government will tackle long-term unemployment by supporting Universal Credit claimants to find work while strengthening work search requirements for job seekers through all stages of their Universal Credit claim.
As a result of these reforms, no claimant should reach 18 months of unemployment in receipt of their full benefits if they have not taken every reasonable step to comply with Jobcentre support.
The plans to tackle long-term unemployment include:
Testing Additional Jobcentre Support in England and Scotland – testing how intensive support can help claimants into work who remain unemployed or on low earnings after 7 weeks into their Universal Credit claim.
Extending and expanding the Restart scheme in England and Wales for 2 years – expanding tailored, intensive support to people who have been on Universal Credit for more than 6 months rather than 9, helping them to tackle barriers to entering employment through coaching, CV and interview skills, and training. The scheme will be extended for two years until June 2026.
Introducing a claimant review point – Universal Credit claimants who are still unemployed after the 12-month Restart programme will take part in a claimant review point: a new process whereby a work coach will decide what further work search conditions or employment pathways would best support a claimant into work. If a claimant refuses to accept these new conditions without good reason, their Universal Credit claim will be closed.
Rolling out mandatory work placement trials – through the claimant review point, claimants who have not yet moved into work by the end of Restart will be required to accept a job or to undertake time-limited work experience or other intensive activity to improve their employability prospects. Failure to do so at this stage will lead to immediate sanction, with the full removal of the Universal Credit standard allowance.
Stricter sanctions for people who should be looking for work but aren’t – including:
targeting disengaged claimants by closing the claims of individuals on an open-ended sanction for over six months and solely eligible for the Universal Credit standard allowance, ending their access to additional benefits such as free prescriptions and legal aid;
rooting out fraud and error using the government’s Targeted Case Review to review the Universal Credit claims of disengaged claimants on an open-ended sanction for over eight weeks, ensuring they receive the right entitlement;
digital tools to track claimants’ attendance at job fairs and interviews.
Plans set out also include expanding key health and employment programmes, to benefit over half a million people over the next five years and help those with mental health conditions stay in or find work:
NHS Talking Therapies – increasing the number of people benefitting from courses of mental health treatment by an additional 384,000 people over the next five years and increasing the number of sessions available.
NHS Talking Therapies provides evidence based psychological therapies including Cognitive Behavioural Therapy (CBT), for treatment of mild and moderate mental health conditions such as depression and anxiety disorders.
Individual Placement and Support (IPS) – aiming to help an additional 100,000 people with severe mental illness to find and keep jobs over the next five years. IPS is an employment support programme integrated in community mental health services. IPS employment specialists:
Work with people accessing the service to find them employment that matches their aims, interests and skills, and offer continued support once they are in post.
Integrate with the mental health team to support the individual with any issues that affect their work and recovery.
Build relationships with employers to negotiate job opportunities.
Universal Support in England and Wales – matching 100,000 people per year with existing vacancies and supporting them in their new role, an increase on the 50,000 people outlined at Spring Budget, also helping people with disabilities and from vulnerable groups.
Participants will access up to 12 months of personalised ‘place and train’ support. The individual will be supported by a dedicated keyworker who will help the participant find and keep a job, with up to £4,000 of funding available to provide each participant with training, help to manage health conditions or help for employers to make necessary accommodations to the person’s needs.
WorkWell – The service announced at Spring Budget 2023 is being formally launched to Integrated Care Systems across England and will help support people at risk of falling into long-term unemployment due to sickness or disability, through integrated work and health support. Integrated Care Systems across England will be supported to develop a localised work and health strategy, and then services will be provided in approximately 15 pilot areas.
Secretary of State for Health and Social Care, Victoria Atkins, said:“We know that tailored work and health support initiatives can help break down the kinds of barriers that can make finding and staying in a job more difficult for those with mental health conditions.
“Backing them with further investment means they’re more widely available, enables personalised help and will get thousands back to work by overcoming any issues that may be preventing them from fulfilling their career potential.”
Kate Shoesmith, Recruitment and Employment Confederation (REC) Deputy Chief Executive, said:“Today’s announcements will help the Restart scheme keep making a real difference to people’s work and life chances.
“It contributes to efforts to overcome our labour and skills shortages and to further growing our economy. Bringing public and private employment services together is vital to get people into work and not look back.
“Our own award-winning Restart scheme, which sees recruiters work with employability services provider Maximus, has helped place 1700 long-term unemployed people into work since 2021.”
‘Someone needs to be honest: your plan is not working, we have endured record election defeats, your resets have failed and we are running out of time. You need to change course urgently’ – Braverman letter to PM Rishi Sunak
IN FULL: Suella Braverman’s scathing letter to PM following her sacking:
A group of students from Scotland’s leading independent day and boarding school for boys, Merchiston Castle School, spoke at the Houses of Parliament in October as part of the British International Education Association’s Youth STEM Forum.
Five of Merchiston’s students were selected to speak at the Forum after winning the prestigious Sustainable Building Design Award in the British International Education Association’s international STEM competition.
Competing with hundreds of other schools from across the globe, including Poland, Pakistan, Canada and Spain, the Edinburgh pupils’ extensive research, pragmatic approach and pioneering design saw Merchiston receive the prestigious STEM award.
Fuelled by predictions that much of Leith will succumb to flooding by 2030, the boys designed a versatile, flood-resistant yet energy-efficient building.
The comprehensive final report showcased a meticulously crafted solution that could be adapted to diverse global locales, demonstrating the groups’ creativity, foresight, and pragmatism in addressing the climate emergency.
Mrs Chapman, Merchiston’s MerchiSTEM coordinator, said of the win:“The British International Education Association STEM competition allows pupils to come up with innovative solutions to real-world problems.
“This draws on and further develops a variety of skills our pupils already have, such as primary and secondary research, report writing, analysing information and visual presentation methods.
“Merchiston’s extracurricular STEM group, MerchiSTEM, embraced the challenge wholeheartedly, and we are incredibly proud of all they have achieved. Speaking at the Houses of Parliament about their design proposal was an incredible opportunity, and one I am sure the boys will not forget for some time!”
Fergus W, a member of Merchiston’s winning team, described the win as“incredibly rewarding”.
He added: “Speaking at the Houses of Parliament was a huge privilege, and we were very proud to be there – and grateful to our teachers for their support.
“As young people, we think it is very important for us to share our opinion on serious, current issues such as Climate Change as this will impact our future.
“We hope that we are listened to and considered in any future planning to do with sustainability so that we can contribute to planning and preparing for our future.”
