Empowering the future of medical research

MEDICAL RESEARCH SCOTLAND INSPIRES OVER 1,400 YOUNG PEOPLE WITH LIVE-STREAMED EVENTS

Medical Research Scotland, Scotland’s largest independent medical research charity, has helped over 1,400 young people across Scotland connect with the country’s leading scientists and academics to learn about further education and careers in medical science.  

The Medical Research Scotland virtual academy has had a significant impact on the education and career prospects of pupils across Scotland. With participation from over 1,400 students from 36 schools spanning from Aberdeen to the Scottish Borders, the academy has successfully engaged students with an interest in STEM subjects. The primary goal for the academy is to address the shortage of STEM skills in Scotland by providing students with interactive experience and exposure to medical research. 

S4, S5 & S6 pupils from schools across Scotland joined each Friday morning for a month of live streamed weekly interactive lessons, which were broadcasted straight to their science classrooms, allowing pupils to watch from the comfort of their own learning environments. Throughout the course, students were treated to a range of inspiring and insightful presentations from scientists, lecturers, and PhD students whose studies were funded by Medical Research Scotland.  

The academy is a free tool that was delivered virtually and is also available to be streamed on demand making it a versatile resource that can be utilised throughout teaching schedules.

One school that benefitted from the Medical Research Scotland Academy virtual webinar series was James Gillespie’s High School in Edinburgh.

Pupils here gained the opportunity to learn about medical research into viruses, pharmaceuticals, how medical research was an integral part of combatting the global pandemic and much more from previous and present PhD students from the University of St Andrews, University of Aberdeen, Heriot-Watt University and the University of Dundee.  

Iain Coltart, Head of Science at James Gillespie’s High School, said: “I am thrilled to see the incredible impact of the Medical Research Scotland Academy on our pupils.

“Through this programme, our students have gained invaluable insights into cutting-edge medical research, engaging with leading experts in the field and deepening their understanding of scientific concepts.  

“The learning experience and exposure to real-world medical research has ignited their passion for science. We are grateful for this unique opportunity that has empowered our students and inspired them to pursue careers in the field of medical research.” 

Professor Heather Wallace, Chair of Medical Research Scotland, said: “As Chair of Medical Research Scotland, I take pride in Scotland’s rich heritage of producing world-class research scientists who have made ground-breaking discoveries and contributed to global health advancements.  

“The goal of the Medical Research Scotland Academy is to inspire and foster connections between the next generation of aspiring medical professionals and valued academics in Scotland. We have witnessed the immense enthusiasm for medical science among school leavers from various schools across the country, and it is truly gratifying to see.” 

Medical Research Scotland is dedicated to advancing health in Scotland and beyond through the support of cutting-edge research aimed at enhancing the diagnosis, treatment, and prevention of diseases.  

To join us in our mission, please visit our website at: 

medicalresearchscotland.org.uk 

and explore ways to contribute. 

If you would like to view this year’s Medical Research Scotland academy webinars, please visit: medicalresearchscotland.org.uk.  

Foreign Secretary visits Glasgow 

  • Foreign Secretary James Cleverly visited Scotland one year on from COP26 in Glasgow. He went to the University of Strathclyde to meet scientists and engineers developing lower cost, recyclable battery tech
  • UK government funded research aims to improve clean energy access for 25 million of world’s poorest people and save nearly 2.5 million tonnes of carbon emissions
  • Foreign Secretary also visited the Foreign, Commonwealth & Development Office’s joint HQ in East Kilbride, which employs almost 1,000 staff in Scotland

Foreign Secretary James Cleverly met with scientists and engineers developing revolutionary battery technologies in Glasgow – a year on from world leaders gathering in the city for the COP26 climate summit.

The Foreign, Commonwealth & Development Office (FCDO) is supporting the Faraday Institution and researchers from the University of Strathclyde and the University of St Andrews, through its Transforming Energy Access (TEA) programme to help offer lower cost, more recyclable battery technology to developing countries.

The UK government announced £126 million of new scale-up funding for TEA during Energy Day at COP26 – focused on reducing carbon emissions by 2.5 million tonnes and securing better access to clean energy for 25 million people.

Since TEA was launched in 2015, it has provided 16 million of the world’s poorest people with improved access to clean energy and generated 96,000 green jobs.

The Foreign Secretary also visited the FCDO’s joint HQ at Abercrombie House, in East Kilbride, where almost 1,000 staff are at the heart of shaping and delivering UK foreign policy on issues such as climate change, including through the TEA programme.

Foreign Secretary James Cleverly said: “Today’s visit is hugely important for me, to see first-hand how people in Scotland are building on the legacy of the UK’s COP Presidency in Glasgow to make progress in the fight against climate change.

“Scotland is famous as an innovation superpower. It has given the world the television, telephone and penicillin, so it was wonderful to learn how Scottish scientists are continuing this rich tradition to develop the revolutionary new batteries of the future fuelled by cleaner energy.

“The UK government is proud to support vital work at the universities of Strathclyde and St Andrews which will help developing countries to access battery technologies to drive green growth and give millions a ladder out of poverty.”

Nearly a tenth of the world’s population – 733 million people – do not have access to the electricity they need to light their homes, refrigerate their food, or keep cool in rising temperatures. Around 2.4 billion people rely on dirty biomass fuels such as charcoal, firewood, or animal waste for cooking.

The Foreign Secretary used his COP26 anniversary visit to witness the start of refurbishment work at the FCDO’s joint HQ in East Kilbride.

The Foreign Secretary was shown a research project led by the University of Strathclyde, which is developing a low-cost battery which is expected to last longer and be more easily recycled.

St Andrews demonstrated battery technology made from common salt, which could enable a move away from materials such as lithium and cobalt which are more expensive, rarer and harder on the environment to source.

Both technologies are expected to be ready to test this year.

Miniature vertical farms travel the country as Dandelion’s cubes tour begins

Dandelion’s cubes are going on tour, starting on top of the iconic Calton Hill in Edinburgh. Special cargo bikes, featuring Dandelion’s unique ‘growing cubes’ called ‘Cubes of Perpetual Light’, will be touring Scotland in Dandelion’s latest initiative to bring music, nature, art, science, community food growing and more, to as many people as possible.

The Cubes Bike Tour forms part of Dandelion, a major creative programme demonstrating the power of collective action through an ambitious ‘grow your own’ initiative that aims to reach hundreds of thousands of people throughout Scotland and further afield this summer. 

The creative programme has been following the arc of the growing season, spanning from April to September 2022, bringing together music and art with science and technology to inspire people to ‘Sow, Grow and Share’ music, food, ideas and stories.

Commissioned by EventScotland and funded by the Scottish Government,  Dandelion is Scotland’s contribution to UNBOXED: Creativity in the UK.

A touring fleet of cargo bikes displaying Dandelion’s growing cubes – miniature vertical farms – will travel the Highlands and Lowlands throughout August.

Four custom-made, electrically assisted bikes – each carrying a cube – will visit ten towns and cities, stopping at school playgrounds, green spaces, town centres, and Dandelion’s Unexpected Gardens, among other locations.

The bikes team will also be giving away free seeds to encourage people to grow their own food. As we come to grips with the impacts of climate change, the need to travel sustainably have never been more important, and the cargo bikes show one way to what is possible.

The bikes also embed active travel at the core of the tour by cycling across the country, as Scotland prepares to host the UCI Cycling World Championships in 2023.

The 1m x 1m cubes are designed to foster accelerated plant growing and have been developed to grow hundreds of seedlings under LED light, combining design craft, traditional horticultural expertise and technological innovation. 

The Dandelion team will also be giving away free seed packets and sharing their expertise, so that everyone can grow their own herbs at home and also find out more about Dandelion’s Harvest celebrations in September.

At each stop, the cubes will play new music specially commissioned for Dandelion by Scottish and international artists, inspired by the natural world and can only be heard at the sites, including Vendanth Bharadwaj, Arooj Aftab & Maeve Gilchrist, 2022 Mercury-nominated Fergus McCreadie, Ravi Bandhu, Trio Da Kali, and amiina & Kathleen MacInnes.

Featuring programmable, immersive lighting integrated with speaker systems designed to best showcase the new music playing from the cubes. Each new music piece is commissioned by Dandelion with additional support for international work from British Council Scotland.

Neil Butler, Director of Festivals and Events at Dandelion, said: ‘We can’t wait for the Cubes Bike Tour to begin. It’s a great way to share Dandelion’s message and reach people in locations throughout Scotland.

“The bikes will be travelling all over the country so we’d love to see people coming along to witness some of the magic, get seeds to grow your own at home and hear more about our upcoming Harvest celebrations.’

Paul Bush OBE, Visit Scotland Director of Events said: “The Dandelion programme is creating an incredible array of events across Scotland this summer, each finding unique moments to connect with people all over the country through growing.

“The Cubes Bike Tour is another engaging example of this, taking Dandelion right into the heart of locations right across Scotland to be enjoyed by locals and visitors alike.

“It’s also fantastic to see events like this embed active travel as part of their programme, and it’s particularly exciting to see biking at the core of this tour as Scotland gears up to celebrate cycling on the world-stage in one year’s time, hosting the 2023 UCI Cycling World Championships”.

Cosmo Blake, Network Engagement Manager at Sustrans Scotland “We are delighted to be able to support Dandelion by supplying four cargo bikes for the Cubes Bike Tour this August.

“By utilising the National Cycle Network, the UK-wide network of signed paths and routes for walking, wheeling and cycling, the tour will be able to reach communities sustainably. With the ever-present impacts from climate change, the importance of both food and transport sustainability are becoming more and more relevant.

“Bringing together active travel, growing, and the arts is a fantastic way to demonstrate the huge breadth of possibilities of cycling for transport as well as for leisure.”

The Cube Bikes will be passing through the places below:

Edinburgh, Tue 2 August

1pm, Edinburgh Botanic Gardens

4pm, Unexpected Garden, Lauriston Farm

Hawick, Wed 3 August

4pm, Hawick Museum, Wilton Lodge Gardens

Stranraer, Fri 5 August

1pm, Unexpected Garden, Harbour Street

Greenock, Sat 6 August

10.30am, Battery Park and along the esplanade

11.30am, Beacon Arts Centre

2pm, The Drying Green, Inverkip Road

Glasgow, Sun 7 August

10.00am, Govan Cross

12noon, Glasgow Science Centre

Forres, Tue 23 August

1pm, Market Square

7pm, Grant Park

Inverness, Wed 24 August

5.30pm, City Centre

Alness, Thu 25 August

Schools tour only

Wick, Fri 26 August

11am, Harbour tour

1pm, Market Square

Thurso, Sat 27 August

1pm, Town Centre

7.30pm, Unexpected Garden

Further locations to be announced throughout August.

For more information and location updates, please see: www.dandelion.scot

Dandelion is commissioned by EventScotland, funded by the Scottish Government and is part of UNBOXED: Creativity in the UK. The bikes were commissioned for Dandelion by Sustrans. The Cube Bikes Tour route will follow the National Cycle Network where available. https://www.sustrans.org.uk/national-cycle-network/

Mobile air pollution exhibit goes on display at Leith Library

A mobile exhibit, highlighting the science and issues around air pollution and air quality, is on display in Edinburgh this summer.

The Scottish Environment Protection Agency (SEPA) and the Glasgow Science Centre launched the touring exhibition in 2020, aiming to highlight the importance of air quality. It will be on display until the end of August at Leith Library.

The interactive exhibit encourages visitors of all ages to think about their local environment and the quality of the air, how poor air quality can affect them and their family and how we can all help to improve air quality through our daily choices. The interactive exhibit also uses a bespoke tool which allows visitors to share their thoughts on the environments they live and work in, and what can be done to improve air quality.

The exhibit uses a simulation model to control traffic and allow users to experience how different types of transport contribute to air pollution. At the same time, the interactive display provides information on the various sources of air pollution and how it can affect our health and wellbeing.

Dr Colin Gillespie, SEPA’s Air Modelling Unit Manager, said: “Reducing air pollution and its associated health impacts is a challenge we should all be mindful of. We all contribute to sources of air pollution through our day-to-day activities and all breathe the same air, so we all have a part to play in improving air quality, no matter how small our actions may seem.

“This mobile exhibition highlights how individuals can take steps to help improve the quality of life both for ourselves and our wider communities and the simulation demonstrates the different ways the quality of the air we breathe can be impacted.”

Transport and Environment Convener at The City of Edinburgh Council, Councillor Scott Arthur, said: “This fascinating and engaging exhibition will really get people thinking about the impacts of poor air quality on our lives, and the choices we can make to limit this. 

“Earlier this year I was proud to launch the Low Emission Zone in Edinburgh as this will reduce air pollution across the city. This is just one of a number of tools the Council is using to tackle poor air quality, from improvements to its vehicles to better infrastructure supporting cleaner modes of transport like walking and cycling, and for Leithers the Tram to Newhaven. What’s more, people using Lothian Buses can be reassured it has one of the cleanest fleets in the UK. 

“Visiting this interactive exhibition at Leith Library will provide an insight into the need to make these kinds of changes for the good of all in our city.”

Dr Gillian Lang, Director of Experience Development at Glasgow Science Centre, said: “We are delighted to have been able to partner with SEPA on developing this touring exhibition to raise awareness of the science and issues around air quality.

“The exhibition was at Glasgow Science Centre during COP26 and has toured to Aberdeen Science Centre where it has been seen by over 16,000 people.”

The mobile exhibition is part of a larger educational package which SEPA has developed with Glasgow Science Centre, aiming to highlight the importance of air pollution and the impacts it can have on our health and the environment.

In 2017, SEPA and the Glasgow Science Centre developed a larger, permanent installation which was originally commissioned by the Scottish Government as part of the Cleaner Air for Scotland (CAFS) strategy, encouraging an interactive way to explore the science behind air pollution.

The mobile exhibit is a development of this work and is now available to tour individual local authority areas.

Anyone interested in finding out more information on how to bring the exhibit to their area can contact SEPA via AirQuality@sepa.org.uk.

Doctor Who Worlds of Wonder: Science exhibition lands in Edinburgh

The Scottish premiere of Doctor Who Worlds of Wonder will take place at the National Museum of Scotland in Edinburgh this December.

This ground-breaking new exhibition, which runs from 10 December 2022 to 1 May 2023, will explore the science behind the global hit television series Doctor Who and will give fans a chance to experience the Doctor’s adventures from a scientific perspective.

Produced by leading experiential design experts Sarner International under license from BBC Studios, this new exhibition invites fans of all ages to explore the role science has played in the world’s longest running action-adventure show. The eight zones set within this educational exhibition cover a diverse selection of exciting scientific topics while drawing in content from across the full canon of Doctor Who

A range of hands-on immersive experiences and interactive features take visitors on a journey through Cosmic Curiosities, a TARDIS Tech room and the science behind time travel asking whether it really is possible, as well as the Monster Vault, where you can get up close with some of the weird and wonderful characters that have graced our screens.

Doctor Who Worlds of Wonder will offer a thrilling exploration of science for both established fans of the TV show and newcomers alike. The exhibition premiered at National Museums Liverpool’s World Museum, where it will run until 30 October.

Alison Cromarty, Head of Exhibitions & Design at National Museums Scotland, said: “We are tremendously excited to be bringing this exhibition to Scotland.

“From the wonder of the science fiction of the TV show to our present-day understanding of the big scientific topics it touches on, there is something for everyone.”

Ed Cookson, Projects Director, Sarner International: “For almost 60 years Doctor Who has been exploring mind-bending scientific developments.

“The iconic characters, monsters, stories, and settings of the television series provide a perfect guide through the wondrous worlds of space, time and science.”

Doctor Who has strong Scottish connections. To date three Scots have played the role of The Doctor, Sylvester McCoy, David Tennant and Peter Capaldi (the Seventh, Tenth and Twelfth Doctors respectively) with a fourth, Ncuti Gatwa, recently announced as the new Doctor.

Other notable cast members have included Companions Karen Gillan and Neve McIntosh as well as Michelle Gomez as Missy (The Master), with Alan Cumming having also appeared recently as King James VI & I.

Another Scot, Steven Moffat, was showrunner from 2008 to 2017.

The show has featured several other Scottish icons. The Loch Ness Monster appears in 1975’s Terror of the Zygons with Tom Baker, while the Picts featured along with the 9th Legion of the Roman army in 2017’s The Eaters of Light (which starred Peter Capaldi and Michelle Gomez).

Other episodes set in Scotland include 2006’s Tooth and Claw, set in the Highlands and Under the Lake/Before the Flood (2015), set in Caithness.

The National Museum of Scotland is supported by players of People’s Postcode Lottery in mounting the exhibition.

Tickets for Doctor Who World of Wonder will go on sale this autumn at:

www.nms.ac.uk/doctorwho.

Get set for Gadgeteers: join the Summer Reading Challenge 2002

Get ready for Gadgeteers, arriving online and in your local library this summer.

Science is all around you! What do you love doing? Are you a brilliant baker? Or a mega music fan? Are you the tech wizard amongst your friends? Join the Gadgeteers for the Summer Reading Challenge to discover the amazing science and innovation behind the world around you, including some of your favourite things!

Curious? Perfect! Your imagination can unlock endless possibilities… We’re teaming up with Science Museum Group for a very special science-themed Challenge that will inspire you to use your imagination and creativity!

Gadgeteers will feature amazing books, awesome rewards, and plenty of ideas for cool experiments and activities to discover the science all around you. The Challenge will be brought to life by top children’s writer and illustrator Julian Beresford.

Are you excited to join the #Gadgeteers this summer? Keep an eye on our blog for all the latest Summer Reading Challenge news!

New £4.25 million grant kick starts UK-wide collaborative research effort to end motor neuron disease

£1 million for MY NAME5 DODDIE Foundation

·        £4.25 million research grant has been awarded that seeks that seeks to discover meaningful MND treatments within years, not decades  

·        Grant awarded by charities LifeArc, MND Association, My Name’5 Doddie Foundation and MND Scotland, together with government research organisations Medical Research Council (MRC) and National Institute for Health and Care Research (NIHR)

·        Funding awarded to researchers from King’s College London, University of Sheffield, University of Liverpool, University College London, University of Oxford and University of Edinburgh to establish a new UK-wide motor neuron disease (MND) research partnership to address problems hindering progress

·        Funding is a springboard for the MND community to develop plans for further ambitious and large-scale research projects, attract significant investment for MND, and encourage more centres to join the scientific mission to find treatments and ultimately a cure for MND

·        Generosity and fundraising efforts of charity supporters have played a big part in making this partnership a reality.

Global MND Awareness Day: A group of charities and government research organisations has awarded £4.25 million to MND experts at six UK universities to kick start collaborative efforts to end motor neuron disease (MND).

This new ‘MND Collaborative Partnership’ brings together people living with MND, charities LifeArc, MND Association, MND Scotland and My Name’5 Doddie Foundation, government bodies Medical Research Council (MRC) and National Institute for Health and Care Research (NIHR), with researchers from King’s College London, University of Sheffield, University of Liverpool, University College London, University of Oxford and University of Edinburgh.

The partnership team will work together to find solutions to address problems currently hindering MND research and seeks to discover meaningful treatments within years, not decades.

Members of this new UK-wide MND research partnership will work together and pool their expertise over three years to:

  • coordinate research effort and deliver maximum impact for people with MND
  • develop better tests to measure MND progression and that allow doctors to compare different drugs
  • improve MND registers so doctors can collect detailed, high-quality data about the disease, and understand which patients are most likely to respond to a particular drug and therefore recommend them for the trials most likely to benefit them
  • support people to take part in clinical trials more easily
  • develop more robust lab tests and models of disease to enable scientists to test theories about the disease and a pipeline of potential therapeutic agents that could ultimately be used as MND treatments.

They will also launch a major new study involving 1,000 people with MND from across the UK to better understand disease progression and how people respond to new and existing treatments.

MND (also known as amyotrophic lateral sclerosis, or ALS) is a devastating neurodegenerative disease affecting the brain and spinal cord. People progressively lose nearly all voluntary movement and need complex care, and around half of those diagnosed die within two years.

Six people are diagnosed with MND every day in the UK and the condition affects around 330,000 across the world. One person in every 300 will develop MND. The only licensed drug for MND in the UK has a modest effect on extending life – but no treatments are available that can substantially modify disease or cure the condition.

Professor Ammar Al-Chalabi, co-director of the research programme and Professor of Neurology and Complex Disease Genetics at King’s College London and Director of King’s MND Care and Research Centre said: “Our goal is to discover meaningful MND treatments within years, not decades. This landmark funding will bring the UK’s major MND research centres together for the first time in a coordinated national effort to find a cure.

“We now have a much better understanding of MND, so we must take this opportunity to accelerate development of new treatments and work together to move this knowledge into the clinic and help people affected by this devastating disease.”

Dr Catriona Crombie of LifeArc, the charity which has coordinated efforts from all funders to deliver this landmark MND Collaborative Partnership, said: “Over recent years, scientists have made great progress in MND, and this has opened up several promising avenues that could ultimately make a difference to patients.

“But there are some barriers hindering progress. For the first time, the MND community – that’s patients, funders, scientists and doctors – have come together to work out the problems and plan a way forward. As funders we are really excited at what this exceptional group of people could achieve for those affected with MND.”

David Setters, who is living with MND and has been involved in shaping the partnership said: “We welcome this collaboration, which paves the way for the £50 million government investment promised in November 2021, focused on making the first meaningful treatments for MND available within years, instead of decades. 

“It brings real hope to those of us living with MND to see our leading neuroscientists and charities coming together in this way. The prospect of easier access to clinical trials and the most promising therapies being fast-tracked gives us a much-needed boost and brings a real sense of purpose to the community.”

Professor Christopher McDermott, one of the co-directors of the research programme and Professor of Translational Neurology at the Sheffield Institute for Translational Neuroscience (SITraN) said: “We believe that by combining and coordinating our expertise, we will be more effective than if we work on projects in isolation.

“This partnership will provide the infrastructure to attract additional MND funding and enable further MND centres and researchers to join forces in the national effort to find effective treatments for MND. The partnership is the first step towards our goal to establish a national MND institute.”

Health and Social Care Secretary Sajid Javid said: “Motor neuron disease has a devastating impact on those who are diagnosed, their families and loved ones – but there is hope. 

“This new partnership is a highly ambitious approach which will drive progress in MND research and, backed by £1 million of government funding, will bring the MND research community together to work on speeding up the development of new treatments.The collaboration across government, charities, researchers, industry and people with MND and their families will take us one step closer to one day achieving a world free from MND.”

The Partnership was formed in 2021 to coordinate and pool funding for research into MND to speed up progress and help research to move towards the clinic and ultimately reach patients faster.

Funding for the MND Collaborative Partnership research grant totals £4.25 million and contributions are as follows: LifeArc (£1 million), MND Association (£1 million), My Name’5 Doddie Foundation (£1 million), MND Scotland (£250,000), Medical Research Council (MRC) (£500,000) and National Institute for Health and Care Research (NIHR) (£500,000).

Scientists awaken viral response to target bowel cancer

New research has identified the role of the immune response within bowel cancer tissue, which could lead to new lifesaving treatments for bowel cancer patients.

The study at Queen’s University Belfast analysed over 1,000 tumour samples from patients diagnosed with bowel cancer. Through analysing the visual appearance of the tumour as well as its genetic make-up, the researchers were then able to test how the immune cells within the tumour responded to different treatments in the laboratory.

The study showed that stimulating a viral-like response within a tumour can reawaken the patient’s own immune system to detect and kill cancer cells. This immune response, similar to a person’s general response to an infection, plays an important role in controlling tumour spread in some bowel cancer patients.

Although in early stage research, it is hoped that this personalised approach to treatment for bowel cancer patients could lead to increased survival rates. The research team will now focus on developing clinical trials, with the aim to treat patients within the next five years.

Dr Philip Dunne, Senior Lecturer in Molecular Pathology at the Patrick G Johnston Centre for Cancer Research at Queen’s and senior author of the study, commented: “In order to identify the most appropriate treatment options for cancer patients, our work combines features from the tumour’s visual appearance down the microscope with information about changes in the genetic make-up of the person’s tumour.

“We have found that stimulating a subset of immune cells to react in the same way that they would to a virus can reactivate multiple steps within the immune system. In cancer patients with early stage tumours that remain localised to the bowel, this enables the immune system to attack cancer cells and reduces the risk of the disease spreading.”

Queen’s PhD student and first author on the study, Shania Corry, explains: “Our findings show that a viral-like response within a tumour can reawaken the patient’s own immune system to detect and kill cancer cells, an approach that has shown remarkable effectiveness in our tumour models.

“We used a synthetic analog of double-stranded RNA, which in many ways is similar to a non-specific vaccine. It looks like a virus to the immune cells though it doesn’t contain any viral replication material. This is a really exciting development, and we hope that this approach will now lead to new treatment options for patients with bowel cancer.”

Bowel cancer is the 4th most common cancer in the UK, with around 42,900 new bowel cancer cases and around 16,600 bowel cancer deaths in the UK every year. The study, published in Gut, to coincide with Bowel Cancer Awareness month, was led by Queen’s University Belfast in collaboration with scientists and clinicians across the UK and Europe as part of two international consortia funded by Cancer Research UK.

Dr Dunne added: “Our study highlights how research can provide clinicians with vital intelligence to make the right treatment decisions for patients in the clinic.

“We have already started the process of developing a clinical trial to test this new “personalised cancer medicine” approach, which has the potential to improve survival and enhance quality of life for bowel cancer patients in the next five years as we develop our work in clinical trials.”

This study used tumour samples from over 1,000 patients diagnosed with bowel cancer, which in turn required analysis and interpretation of the resulting data across an international network of multidisciplinary researchers.

Professor Owen Sansom, Director of the Cancer Research UK Beatson Institute in Glasgow and co-author on the study, said: “This exciting new research demonstrates how cross-disciplinary collaborations, between scientists and clinicians, are essential to ensure we comprehensively characterise a patient’s tumour, allowing us to test novel treatments specifically designed to target the biology of the disease.”

Professor Mark Lawler, Chair in Translational Cancer Genomics and Professor of Digital Health at Queen’s, who co-authored the study said: “This important study demonstrates how scientific research at Queen’s can develop innovative new ways to treat cancer.

“The work pioneered by Dr Dunne’s research team validates our investment in “rising stars” who have the confidence to lead team science initiatives with prestigious international partners, addressing global challenges which will improve the lives of cancer patients.”

Responding to the study, Dr Sam Godfrey,  Research Information Lead at Cancer Research UK, said: “An important goal for beating cancer is to work out how to train our immune systems to recognize the disease and attack it.

“So It is really interesting that we could manipulate one of the defences our bodies use to deal with viruses so that it can tackle cancer.

“Further studies are needed to assess the potential of this approach in patients, but it is an exciting development that could unlock new targeted treatments for bowel cancer.”

The research study was supported by an Early Detection project grant and International accelerator programme, both funded by Cancer Research UK (CRUK), with additional funding from the Medical Research Council (MRC) and the Queen’s University Foundation, a charitable trust that funds the world-class research in Queen’s.

Dynamic Earth helps power the future as Scotland’s Science Centres unite for National Climate Campaign

The National Climate Campaign empowers underserved communities across Scotland with climate change knowledge

Dynamic Earth have delivered a packed programme of events and experiences exploring climate change including the delivery of STEM kits to a local children’s hospital, as part of a National Climate Campaign uniting Scotland’s Science Centres.

The kits, designed for young people, contain a variety of activities and experiments focusing on earth and environmental sciences, with connections to climate change and marine environments.

These boxes give young people the chance to explore connections between ocean depth and pressure, experience augmented reality colouring-in, build their own rope and more, bringing science directly to them wherever they are.

Alongside their STEM kit distribution, Dynamic Earth delivered a series of in-person events and digital programmes reaching over seven thousand people as part of a campaign, building on the legacy of COP26 alongside Scotland’s other science centres.

The centre has been running climate change workshops with community audiences and family learning activities with local primary schools, reaching groups including the Edinburgh Young Carers Project Care for Carers and the Citadel Youth Centre.

Brought together by Glasgow Science Centre, the centres have joined forces to inform, inspire and empower a diverse audience to tackle the climate crisis and ensure the discussion on climate change remains open.

Working together to further climate science education in their communities, the National Climate Campaign saw each centre deliver a coordinated and interactive campaign of over 89 events, reaching over 13,000 members of underserved and underrepresented audiences by the end of March 2022.

The programme strived to make science more relatable and helps learners build up their science skills to understand the world around them.

Elsewhere in Scotland, Glasgow Science Centre have been hosting weekly community visits and film screenings, shining a light on the importance of science in the community and engaging with groups who are unlikely to visit Glasgow Science Centre regularly and can be most affected by climate change and its effect on lifestyle.

In total Glasgow Science Centre have facilitated 16 community group visits this year to the Science Centre, including visitors from Glasgow Disability Alliance, Yorkhill Green Space and African Challenge Scotland.

They have engaged 374 people who may have not visited the centre before, while also offering 3,000 primary school pupils in remote, rural and deprived areas access to their online interactive ‘Learning Labs’.

A highlight from Aberdeen Science Centre’s 20-event programme was last month’s Supper and Science Evening, where families came together to cook an evening meal at Northfield Academy.

While the meal was cooking, Science Centre staff ran a series of climate-themed workshop activities, including one where they recreated an oil spill with feathers and soap, to give the children some hands-on climate science experience.

In Dundee, the team created 150 climate-themed community kits for young people, containing a mini solar-powered windmill as well as other items to show how earth and environmental sciences connect to climate change and marine environments, while also engaging over 1,000 primary school pupils in activities during COP26 Schools Week.

Eilidh Massie, Marketing Director at Dynamic Earth said: “It is so important for people to not only learn about our amazing planet, but also to understand that the Earth’s climate system is something we have taken for granted for too long.

“At Dynamic Earth we’re committed to reminding people, young and old, that we need to act now before the damage is irreversible.

“It has been a fantastic opportunity to work collectively with Scotland’s Science Centres as part of the National Climate Campaign to further these messages.”

Stephen Breslin, CEO of the Glasgow Science Centre said: “We set up the National Climate Campaign to ensure that there is a legacy of climate engagement left behind after COP26.

“We hope that by providing communities across Scotland with our knowledge and resources, we can act as a magnet for climate engagement and help empower young people to make considered decisions and learn what climate change means for them.”

Environment Minister, Mairi McAllan said: “Young people have been among the strongest voices calling for urgent global action to address climate change.

“This campaign will make sure that young people in communities across Scotland continue to play a key role in our journey to becoming a net zero nation, delivering a lasting legacy for COP26, and making their voices heard loud and clear.”

For more information on the National Climate Campaign and Scottish Science Centre’s climate change education programming visit:

https://www.glasgowsciencecentre.org/discover/our-world-our-impact

Edinburgh STEM graduates wanted for fifty fully-paid work placements made available across Scotland

The National Manufacturing Institute Scotland (NMIS) has established fifty fully-paid work placements within manufacturing and technology businesses across the country with the launch of the second round of its Manufacturing Skills Academy’s graduate training programme.

The placements are set to provide graduates with the opportunity to build in-demand skills and experience in the worlds of digital and advanced manufacturing, with positions now available across the Edinburgh region.

Each up to six months in duration, the placements are aimed at recent university and college graduates of a STEM related subject who are unemployed or struggling to find meaningful work due to the impact of Brexit and the COVID-19 pandemic.

Based within new and emerging markets such as green energy, space and renewables, placements are being offered within innovative companies across Scotland.

For example, successful applicants could find themselves working for Edinburgh based Shapespace Ltd, specialising in engineering and manufacturing analytics software, or Mask Logic, using additive manufacturing within product design.

Graduates could also look further afield to the likes of Scotmas Group, specialising in design, development and manufacture of environmentally sustainable disinfection equipment for water treatment, healthcare and food industry, with positions available in a number of companies across Scotland.

This new round of graduate training follows on from the success of the pilot programme launched early last year.

The programme saw thirty graduates recruited and placed with companies across Scotland and the NMIS Group giving valuable on-the-job work experience. A number of graduates have now gone on to secure extended contracts, or full-time employment.

Funded by the Scottish Government’s £20 million National Transition Training Fund (NTTF), the programme has been developed by the NMIS Manufacturing Skills Academy and is one of a number of initiatives designed to support Scotland’s economic recovery, and the transition to net-zero.

Minister for Youth Employment and Training Jamie Hepburn said: “The National Manufacturing Institute Scotland’s Manufacturing Skills Academy is delivering excellent work-based training to help graduates move permanently into high quality jobs in manufacturing.

“Building on the success of last year’s National Transition Training Fund pilot, this is an important opportunity for STEM graduates to access high quality training opportunities right across Scotland.”

Stewart McKinlay, Skills Director at the National Manufacturing Institute Scotland’s Manufacturing Skills Academy said: “We’re delighted we’ve received further support to provide an opportunity to fifty more graduates, now including those from colleges as well as Universities.

“The support from the Scottish Funding Council for the National Manufacturing Institute Scotland’s pilot graduate training programme last year allowed us to place 30 graduates within thriving businesses across the country and the specialist technology centres at NMIS. 

“It was a real success, with a significant number of the employers making permanent job offers to the graduates and other graduates going on to receive multiple offers from other companies based on the strength of their work experience. The aim is to replicate, and improve on this further, in 2022.”

The graduate training programme is now open for applications. Candidates are asked to submit an application form and short video before being matched to potential opportunities with an industry partner.

Speaking about his experience from the 2021 graduate training programme, Mina Hanna, who has now secured a further contract with Opportunity Cromarty Firth and the University of the Highlands and Islands said: “The National Manufacturing Institute Scotland’s graduate training scheme was truly a life changing experience, and I would encourage all manufacturing and engineering graduates to apply. 

“The time that was given to me by so many experienced professionals was an incredible opportunity and I am so grateful to NMIS Manufacturing Skills Academy for allowing me to embark upon a career that I am passionate about.”

NMIS, which is operated by the University of Strathclyde, is also encouraging expressions of interest from companies across Scotland that are interested in being part of the programme and placing a recent graduate.

Renewable Parts placed three graduates within its company last year. Michael Forbes, General Manager of Refurbishment Engineering at Renewable Parts, said: “We were delighted to work with the National Manufacturing Institute Scotland on the graduate training scheme, and with the high standard of applications.

“The business is growing, and the scheme allowed us to recruit for positions where otherwise we may have held off until a little later.

“The placement was almost like a 6-month interview, allowing us to see how the graduates integrated with the existing workforce.”

The applications process for the NMIS Manufacturing Skills Academy graduate training programme closes in early February.

An NMIS Insights online event is also taking place in the coming weeks offering an opportunity to find out more about the programme and hear from previous graduates and companies as they share their experiences.

Details will shortly be available on the event section of the NMIS website.