Chief Medical Officer encourages people to come forward for antiviral trial

National study will test new COVID-19 treatments

New treatment options will see people in the early stages of illness from COVID-19 who are at higher risk of complications access new antiviral treatments.

Antiviral medicines for the treatment of COVID-19 will be evaluated through a new national study called PANORAMIC, run by the University of Oxford. The UK-wide study will prioritise those at greater risk of being severely ill if they test positive for COVID-19. Eligibility for the study is therefore limited to those who meet certain criteria.

The study, starting today, is open to people aged 50 and above, or 18-49 with certain underlying health conditions which make them more vulnerable to COVID-19. They must also have started to experience COVID-19 symptoms within the past five days and have recorded a positive PCR test.

In addition to the study, all people considered as extremely high risk of becoming severely ill with COVID-19, and who have tested positive, will be able to access a monoclonal antibody or, if not appropriate, an antiviral treatment, from 16 December.

In the coming weeks letters will be sent to those eligible with further information. Details on who is eligible can also be found on NHS Inform, and – from 16 December – a dedicated contact number will be available for each health board to provide further information on how to get access to the medicines.

These treatments are in addition to vaccinations which still remain the best way to protect everyone.

Scotland’s Chief Medical Officer Dr Gregor Smith said: “This University of Oxford study will test whether new antiviral treatments for COVID-19 can help people in the early stages of the illness recover faster and therefore reduce the number of people being admitted to hospital.

“The results from the national study will give us a clearer understanding on how antivirals work in the UK population, which will allow the NHS to better plan how to make COVID-19 antivirals available for those who would benefit from them the most. We will provide further detail on plans for wider availability of antivirals in due course.

“I would encourage people in Scotland to take part if they are eligible. You may be contacted about taking part by a health care professional if you have a positive PCR result, or you can register yourself via the Oxford University website www.panoramictrial.org.

“The treatment is tablets taken orally as soon as possible after getting a COVID-19 infection to stop the illness from getting worse.

“Antiviral treatments are in addition to COVID-19 vaccinations – including boosters – and not a replacement. We hope they will help reduce the severity of illness in people who may fall ill even if they have been vaccinated.  

“It remains clear that getting vaccinated is the single most effective step that anyone can take to protect themselves from the most severe disease caused by COVID-19. Anyone who has not yet received their first or second COVID-19 vaccination can check their nearest open access centre on NHS Inform or phone the national vaccination helpline on 0800 030 8013.” 

Further details on the University of Oxford trial and what is involved in taking part is available at www.panoramictrial.org.

Chief Medical Officer urges pregnant women to get vaccinated

“By far the best course of action for you and your baby is to get both doses of the vaccine”

Scotland’s Chief Medical Officer is urging pregnant women to get the coronavirus (COVID-19) vaccine to protect them and their baby.

Following a recent study showing evidence of increased hospitalisations, Dr Gregor Smith is encouraging all expectant mothers to discuss the vaccine with their healthcare professionals so they can make a fully informed choice.

The UK Obstetric Service (UKOSS) published research last month which showed the number of pregnant women being admitted to hospital with COVID-19 across the UK is increasing, with many experiencing acute symptoms.

The report also suggests the Delta variant is associated with an increased risk of severe illness among hospitalised pregnant women.

Dr Smith said: “Firstly I want to thank all our healthcare staff for everything they are doing across Scotland not just in relation to the wider vaccination programme but also for their efforts to ensure good outcomes for women, families and babies during the pandemic.

“We have written to heath boards and GPs to ensure they are aware of all the latest evidence-based advice and guidance to enable them to fully discuss the very clear positive benefits of the vaccine with their patients.

“Recent data shows the number of pregnant women being admitted to hospital with COVID-19 has risen, and that is concerning. Evidence suggests that the Delta variant may be associated with an increased risk of severe illness among hospitalised pregnant women.

“We want all pregnant women to have the information they need to make an informed choice, so if you have any concerns or questions, please speak to your midwife, GP, or go along to a drop-in clinic. By far the best course of action for you and your baby is to get both doses of the vaccine.”

UKOSS study

NOTE: 3,613 new cases of COVID-19 were reported in Scotland yesterday. The trend is upwards – this pandemic is far from over.

Protecting Scotland against COVID

Appeal for those who missed vaccine appointments to come forward  

Anyone who was part of vaccine priority groups 1-9 and missed their original appointment is being asked to come forward to arrange their vaccination.

This includes everyone 50 or over, adults on the shielding list, anyone with underlying health conditions, and unpaid carers.

Invitations have been issued to everyone aged 40 or over, with 30-39-year olds starting to be invited now. In the specific areas of Glasgow affected by the current outbreak, all 18-39 year olds are being invited with older age groups first.

Anyone who believes they should have had a letter by now with details of either their first or second dose should call the national helpline or fill out the missing appointments form on the NHS Inform site.

The system for handling missed appointments has recently been streamlined in order to speed up the process.

More than three million people – two thirds of the adult population – have now received their first dose. However, in response to the new variant currently circulating in parts of the UK, and in line with updated JCVI advice, second doses which are not already scheduled, are being brought forward from 12 weeks to eight weeks across Scotland where supply allows.

Chief Medical Officer Dr Gregor Smith said: “Our vaccination programme has been extremely successful, and we’ve seen very high uptake rates across all age groups. However, we know that there will inevitably be a small number of people who, for a variety of reasons, may not have taken up their original appointment.

Our message to you is clear – it is not too late, and you are still welcome. Please contact us to make an appointment today.

“It continues to be vitally important that everyone takes up the opportunity to get both doses of their vaccination when their opportunity arrives. I want to emphasise that the second dose offers greater and longer lasting protection, and should not be missed.

“Vaccination is crucial in protecting ourselves, our families and communities and helping us on the path back to normality.

“Anyone who missed their original appointment, or thinks they may have been missed, should contact the Vaccination Helpline on 0800 013 8013 or fill out the missing appointment form on the NHS Inform website. They can also help you find other ways to get your coronavirus vaccination if you are unable to leave your home for your appointment on medical grounds.

“People who have been vaccinated should still continue to get tested and engage with contact tracing teams if they are a contact of a positive case. While the latest evidence suggests vaccines provide a high level of protection, they don’t yet provide a guarantee that you can’t still get the virus or pass it on to others around you.”

Catherine Calderwood resigns

Scotland’s Chief Medical Officer Dr Catherine Calderwood resigned from the Scottish Government late last night.

Dr Calderwood had earlier offered an apology for ignoring public health guidelines on not travelling away from home – not once, but twice – at a deeply uncomfortable press conference.

Ms Calderwood’s apology was never going to be enough to appease growing public anger, however. To break your own rules once is perhaps a mistake, but to repeat the offence a week later is quite simply unforgiveable. Scotland’s senior health official had to go – and really should have resigned sooner.

First Minister Nicola Sturgeon tried to protect Ms Calderwood at yesterday’s media briefing, but it later became clear that public furore was not dissipating.

The Chief Medical Officer’s position as one of the most recognised faces of Scotland’s fight against the coronavirus was untenable.

With public confidence draining, Ms Calderwood bowed to the inevitable and tendered her resignation. In a statement issued late last night, Dr Calderwood said: “I am deeply sorry for my actions and the mistakes I have made.

“The First Minister and I have had a further conversation this evening and we have agreed that the justifiable focus on my behaviour risks becoming a distraction from the hugely important job that government and the medical profession has to do in getting the country through this coronavirus pandemic.

“Having worked so hard on the government’s response, that is the last thing I want.

“The most important thing to me now and over the next few very difficult months is that people across Scotland know what they need to do to reduce the spread of this virus and that means they must have complete trust in those who give them advice.  It is with a heavy heart that I resign as Chief Medical Officer.

“I will work with my team over the next few days to ensure a smooth transition to my successor.”

Catherine Calderwood’s actions really could not have come at a worse time. The coronavirus is yet to peak in the UK, and Ms Calderwood had a key role in getting the public health message out to Scots during these hugely difficult times.

The Chief Medical Officer’s departure is undoubtedly a personal blow to First Minister Nicola Sturgeon – it’s a distraction she could well have done without as she leads the country in the great challenges we face.

First Minister Nicola Sturgeon said last night: “Dr Calderwood’s advice to me, to the government and to people across Scotland over the past few weeks has been the right advice. People should continue to stay at home to protect the NHS and to save lives.

“It is however clear that the mistake she made – even though she has apologised sincerely and honourably for it – risks distracting from and undermining confidence in the government’s public health message at this crucial time. That is not a risk either of us is willing to take.

“Catherine has been a transformational CMO, bringing changes to the way medicine is delivered in Scotland and in particular using her experience to bring an overdue focus to women’s health. Also, as I said earlier, her advice to me on Coronavirus will be missed – which is why she will work to ensure a smooth transition in the days ahead.

“While she has made a very serious mistake in her actions, that should not detract from the fact that as CMO she has made a highly valuable contribution to the medical profession and to health in Scotland, and I have no doubt she will continue to do so in future. She leaves office with my thanks and admiration.”

 

Health of the Nation: Personalising Realistic Medicine

Healthcare professionals are being encouraged to deliver a more personalised approach to care by Chief Medical Officer Dr Catherine Calderwood, who has published her fourth annual report: Personalising Realistic Medicine Continue reading Health of the Nation: Personalising Realistic Medicine

Chief Medical Officer calls for move away from “doctor knows best”

The country’s most senior clinician is encouraging patients to get more involved in their treatment and care options. Scotland’s Chief Medical Officer (CMO) Dr Catherine Calderwood is calling for a move away from the “doctor knows best” culture in her annual Practising Realistic Medicine report, which sets out steps to help patients get more involved in their medical consultations. Continue reading Chief Medical Officer calls for move away from “doctor knows best”