Tag: advances in technology

Total-body scanner set to unlock disease insights

Scotland is set to receive its first total-body scanner in a boost to clinical research that aims to improve the detection, diagnosis and treatment of complex, multi-organ diseases.

The Total-Body Positron Emission Tomography (PET) facility, due to be operational in 2024, will capture images of patients’ entire bodies quicker, in more detail and use less radiation than existing scanners.

In combination with data from the other new scanner in London, the Scotland scanner forms part of a new National PET Imaging Platform (NPIP) which experts believe will accelerate the development of new drugs and diagnostics.

The platform, a partnership between Medicines Discovery Catapult (MDC), the Medical Research Council (MRC) and Innovate UK, aims to advance healthcare research and clinical trials, and unlock new treatments for complex diseases like cancer as well as cardiovascular and neurological diseases.

The NPIP Scotland Total-Body PET facility will allow academics to connect to the new platform to share data and collaborate on research.

The scanners are part of a £32 million investment into the ground-breaking technology by the UK Government, through the UK Research and Innovation (UKRI) Infrastructure Fund.

The facility, based at the Royal Infirmary in Edinburgh, will be jointly managed by the Universities of Edinburgh and Glasgow.

NPIP’s Total-Body PET scanners have higher sensitivity than current technology and will reveal new insights into biology and disease.

PET scanning is a non-invasive imaging technique that can detect diseases’ early onset.

Current PET technology leaves large sections of the human body out of the field of view, requiring the patient to be repositioned multiple times to achieve a full-body view.

Supplied by Siemens Healthineers, the two Total-Body PET scanners will capture superior images of a patient’s entire body in near real-time.

The new scanners are also faster, exposing patients to much lower doses of radiation, meaning more patients – including children – can participate in clinical trials to improve understanding of diseases.

The speed of Total-Body PET scanners mean that NPIP will be able to facilitate more patient scans, enhancing the scale and impact of clinical research projects.

This richer picture of human health will help researchers to develop new diagnostics, improve the quality and speed of drug discovery, and bring them to market quicker to benefit patients.

NPIP’s network of infrastructure and intelligence will provide a complete picture of patients and how they respond to new drugs and treatments.

Uniquely, it will also connect insights from many research programmes and trials. In doing so, it will begin to build a rich bank of data that the PET community can access for the benefit of patients.

Professor David Newby, The University of Edinburgh, Co-Director of the NPIP Scotland Centre, said: “The Scotland Total-Body PET facility will bring together academics, industry and clinicians to create an integrated and accessible national PET facility for the benefit of patients across Scotland and the north of England.

“The Total-Body PET scanner will allow us to examine patients in ways that haven’t been possible before, propelling medical innovation and discovery, and ultimately improving the detection, diagnosis and treatment of complex diseases, including cancer.”

Dr David Lewis, University of Glasgow, Co-Director of the NPIP Scotland Centre, said: “Total-Body PET scanners are a quantum leap forward in the technology of body scanning, and we are proud that a partnership between the University of Edinburgh and the University of Glasgow will jointly manage one of the first of these cutting-edge scanners in the UK.

“The Scotland Total-Body PET scanner will be a catalyst for innovative new research and cross-sector collaboration, ultimately benefitting patients by improving our understanding of complex diseases.”

Dr Juliana Maynard, Director of Operations and Engagement for the National PET Imaging Platform and Head of Translational Imaging at Medicines Discovery Catapult, said: “PET scanning is nothing short of transformational for patients who need it the most.

“Total-Body PET scanners can detect serious diseases with unprecedented speed and accuracy. NPIP will allow the kind of collaboration in imaging research the likes of which the UK has never seen before. It means that, collectively, we can power forward drug discovery with renewed confidence and drive world-leading capabilities in detection, diagnosis, and treatment.”

MOT? More like DIY!

Drivers Urged to Maintain Cars Themselves

Motorists have been told to maintain their vehicles if proposed changes to MOTs come into force.

Experts from Quotezone.co.uk have warned drivers to ensure their vehicles are roadworthy after proposals to extend the period between tests. 

The proposals have come via a consultation jointly published by the Department for Transport (DfT) and Driver and Vehicle Standards Agency (DVSA), affecting cars, motorbikes and vans. 

Currently, all new vehicles must be tested after they reach three years old, to ensure they do not present a danger to other road users. 

But if the new proposals are adopted, this period will be extended to four years, in line with many other countries across Europe. 

Advances in technology and the increase in popularity of EVs and hybrid cars mean new vehicles are less likely to need major attention at three years old. 

They also suggest that the period between MOT tests could also be extended from one year for newer vehicles. 

While the experts from Quotezone.co.uk welcome the chance for drivers to create savings, safety must always be the number one priority and both the government and the motorists themselves have a duty to ensure their cars, vans and motorbikes are safe to operate. 

Many countries across Europe have the four year policy, and the proposals would bring Britain in line with countries like Belgium, Denmark, France, Italy, Spain and Portugal.

Government analysis shows less frequent MOT tests could save UK drivers around £100 million per year.

Quotezone.co.uk did a sample survey in Northern Ireland – where all vehicles must be tested at a dedicated MOT centre – putting the system under increasing pressure to clear the pandemic backlog.  43% of drivers were said to be waiting over 3 months for an available test date and 59% were driving on the road pass their test due date. 

These proposed changes may alleviate some issues but it’s important to remember 1 in 10 vehicles fail their MOT first time, under the proposal these vehicles would now be on the road for an additional year which some experts fear may increase the number of unsafe vehicles on our roads. 

Quotezone.co.uk Founder Greg Wilson has said: “These proposals to have less frequent MOT tests is likely to put the onus on the driver to more regularly maintain the vehicle and ensure its roadworthy. 

“Whilst of course money saving benefits are great in this economic climate, getting into an accident or driving an unsafe car could result in costs far bigger than a £40 MOT.

“There are several routine checks which drivers can do at home to help their vehicle stay in a safe and roadworthy condition.”

Quotezone.co.uk has provided checks you can make on your car:

  1. Check tyres: 

Before setting off, it is important to check for any cuts or wear. It is also good to check if the tyre pressures are appropriate for the load and condition of the tyres. The minimum and legal limit for tread depth of the tyres is 1.6mm – drivers can insert a 20p into the tread to double check, the tyre thickness should be more than the first line on the coin.

  1. Check lights: 

You need to make sure your indicators, hazard lights, headlights, fog lights, reverse lights and brake lights all work. Having any of these not working or in a temperamental condition could put you, passengers and other motorists at risk.

  1. Check brakes:

The braking system needs to be in good working order. If the car pulls to one side when applying the breaks then this indicates an issue. Look at the handbrake too and ensure it works well, especially on an incline. If you have alloy wheels, it could be possible to do a visual inspection of the brakes without actually removing the wheel.

  1. Check fluid levels:

Keep your screen wash topped up so you can clean dirt off your windscreen and ensure you have good visibility and top up break fluid and oil. 

  1. Check mirrors: 

All mirrors must be secure and free of cracks. If they need replacing you can normally find ones for your car model online, but stay clear of self-adhesive types as these are not durable.

  1. Check windscreen and wipers:

Ensure there is no damage to your windscreen. A chip or crack that exceeds 40mm will actually result in a failed MOT test. On top of the windscreen, the wipers and washers should be functional to ensure good visibility at all times. 

Quotezone.co.uk helps around 3 million users every year find savings on household bills and essentials, including niche items such as motorbike insurance, van insurance and courier insurance.  –