Lothian MSP encourages capital residents to get involved with Covid-19 vaccination trials

Lothian MSP Miles Briggs is encouraging Edinburgh residents to get involved with Covid-19 vaccination trials.

Miles Briggs said: “Phase 3 of Valneva Covid-19 vaccination trials are pivotal for getting the new vaccinations into production.

“Two thirds of adults have had their first dose of a vaccine and a third their first dose, but booster doses will likely be required later in the year.

“The distribution of vaccines to other countries across Europe and globally will also be important, with most countries being behind Scotland and the UK in their vaccine rollout.

“I would encourage anyone over 18 who is interested in being involved with the Valneva vaccine trial to sign up at ukcovid19study.com

In January 2021 we started commercial manufacturing of our COVID-19 vaccine at our site in Livingston, which is a globally qualified manufacturing site for viral vaccines.

We are producing our COVID-19 vaccine on our established Vero-cell platform – leveraging the manufacturing technology for our licensed Japanese Encephalitis vaccine. This video provides a snapshot of manufacturing at our site in Scotland. 

We are also significantly expanding our facilities at Livingston to increase vaccine manufacturing capacity, which is creating new jobs in the area.  

Last month we reported positive data from the Phase 1/2 trial of our inactivated COVID-19 vaccine, which found that it was well tolerated, with no safety concerns identified, and highly immunogenic. 

Alongside NIHR and NHS Research Scotland, we have now initiated a pivotal Phase 3 trial at around 25 sites, including the Western General in Edinburgh.

Unlike earlier COVID-19 vaccine trials, which involved a placebo dose, everyone involved in this trial will receive two active vaccine doses.

Even as existing vaccines are rolled out, there is an ongoing need for people to volunteer for vaccine research.

If you’re over 18 and haven’t had a #vaccine yet, you could be eligible to take part in the Phase 3 trial of Valneva’s inactivated #COVID19 vaccine. Find out more at: ukcovid19study.com #BePartofResearch

The #Valneva vaccine being manufactured in Livingston is the only inactivated #COVID19 vaccine in development in Europe and it’s now being trialled in #Edinburgh.

To find out about the #vaccine and getting vaccinated, take a look at: ukcovid19study.com

As we roll out existing #COVID19 vaccines, experts are working on new ones & boosters to protect us over time. Crucially, volunteers are still needed for trials.

To find out about the Valneva #vaccine trial, taking place in Edinburgh, visit: ukcovid19study.com

UK government secures additional 40 million doses of Valneva vaccine

  • Deal means the UK has now secured early access to over 400 million total doses of vaccines for 2021 and 2022
  • 100 million doses of Valneva vaccine have now been secured
  • UK Government boosts Scotland vaccine production powerhouse at Valneva’s site in West Lothian, supporting 100 highly-skilled jobs

The UK Government has today signed a deal for a further 40 million doses of Valneva’s promising vaccine candidate. The latest deal will bolster long-term vaccine production in Scotland and brings the total UK vaccine portfolio to 407 million doses over the next two years.

The decision to purchase 40 million extra doses is based on the UK’s strategy to take a wide approach, using different technologies and viral targets to ensure the UK has the best chance of securing access to successful vaccines as quickly as possible. It will also give the UK future flexibility should we need to revaccinate any of the population.

The UK Government has invested a multi-million sum in Valneva’s manufacturing facility in West Lothian, which began manufacturing vaccine doses last week and is already raising Scotland’s profile in the international fight against Covid-19.

The site is already supporting 100 new highly-skilled local jobs for scientists and technicians.

Valneva’s coronavirus vaccine candidate is currently in phase I/II trials and will still need to meet the necessary safety and effectiveness standards and receive regulatory approval from the UK Medicines and Healthcare products Regulatory Agency (MHRA) before it is rolled out at the end of the year.

However, if it is approved, manufacturing at risk now will mean that the UK can roll the vaccine out across the country quicker.

Business Secretary Kwasi Kwarteng said: This latest deal is yet another weapon in our national arsenal against this terrible disease, and will ensure we have sufficient supplies to protect the British public in 2021 and beyond.

“Backed with major investment from the UK Government, Valneva’s site in Scotland will be a vaccine production powerhouse, working flat out to ensure we can quickly deploy jabs across the UK if their candidate is approved, while supporting top quality, local jobs.

Thanks to our incredible UK Vaccine Taskforce, we have now secured a bumper portfolio of over 400 million vaccines, putting our country in an exceptionally strong position to defeat this virus once and for all.”

Vaccines Minister Nadhim Zahawi said: “This deal provides a further boost to the UK’s already-strong vaccine portfolio, and I am enormously proud of all the work which has gone in to securing a vaccine for the UK as soon as possible.

“If approved, Valneva’s vaccine will not only help tackle Covid-19 here in the UK, but aid our mission to ensure there is a fair supply of vaccines across the globe.

“No one is safe till the whole world is safe.”

The Secretary of State for Scotland Alister Jack said: “This deal is an endorsement of the UK Government’s strategy of investing in vaccine development and in the skills of the Scottish life sciences sector.

“I pay tribute to the team in Valneva’s new Livingston manufacturing plant. If the vaccine is authorised by the health regulator, their expertise will play an important role in making the world safer from this virus.”

Health Secretary Matt Hancock said: The UK has developed and invested in some of the world’s most promising vaccines – supporting global efforts to fight this virus.

“The Valneva vaccine showcases the best of Scottish expertise right at the heart of our UK vaccine endeavour, demonstrating the strength of our union and what the UK can achieve when it works together. If the vaccine is authorised by the health regulator, it will be rolled out across the four nations as quickly as possible.”

Interim Chair of the UK government’s Vaccines Taskforce Clive Dix said: “Valneva’s manufacturing site in Scotland is already up and running, ready to supply their promising vaccine as soon as it has proven to be safe, and effective and is approved by the MHRA.

“To best ensure we have enough successful candidates to ensure maximum coverage of the UK population, the Vaccines Taskforce has invested in seven of the most promising vaccines. The further 40 million doses secured through today’s deal significantly bolsters our portfolio and gives us future flexibility should we need to revaccinate any of the UK population.

“I want to thank everyone involved in the development of this vaccine for the hard work that has helped us reach this point and also to pay tribute to those UK citizens who have volunteered to take part in the important clinical trials of this vaccine.”

If it is approved, 60 million doses could start to be delivered to the UK by the second half of 2021, with the remaining 40 million being delivered in 2022.

Valneva’s Livingston site will have the capacity to produce up to 250 million doses annually for shipment across the UK and around the world.

The UK Government is committed to supporting equitable access to vaccines worldwide. The UK is the largest donor to the COVAX facility, the global mechanism to help developing countries access a coronavirus vaccine, and has committed £548 million in UK aid to help distribute 1.3 billion doses of coronavirus vaccines to 92 developing countries this year.

To date, the UK government has invested over £300 million into manufacturing a successful vaccine.

Large-scale coronavirus vaccine manufacturing begins in Scotland

  • Valneva begins large-scale vaccine manufacturing at its Livingston site in West Lothian
  • up to 60 million jabs due to be manufactured by the end of 2021 if the vaccine is approved
  • UK government investment will support 100 new jobs at the site, a doubling of the workforce

This follows a multi-million-pound joint investment in the facility by the UK government last year as part of an agreement in principle to secure early access to Valneva’s vaccine by the end of 2021. 60 million doses have already been secured for the UK, with an option to acquire a further 130 million if the vaccine is proven to be safe, effective and suitable.

This investment will now support 100 new highly-skilled jobs for scientists and technicians at the Livingston facility – doubling the workforce, putting Scotland at the forefront of the UK’s fight against COVID-19, and boosting the UK’s resilience in dealing with current and future pandemics by establishing a permanent vaccine manufacturing base.

Valneva’s coronavirus vaccine candidate is currently in phase I/II trials and will still need to meet the necessary safety and effectiveness standards and receive regulatory approval before it is rolled out at the end of the year. However, if it is approved, manufacturing at risk now will mean that the UK can roll the vaccine out across the country quicker.

Business Secretary Kwasi Kwarteng said: “Thanks to the UK Vaccine Taskforce, we have ordered up to 60 million jabs of Valneva’s promising vaccine if it proves to be safe, effective and suitable in its clinical trials this year.

“By starting manufacturing, we will have a running start at rolling these out as quickly as possible to protect the British public if it receives regulatory approval.

“This facility in Scotland, backed by millions from the Government, will help us beat coronavirus and boost our resilience against future pandemics.”

The new facility establishes a permanent UK capability to manufacture inactivated viral vaccines – one of the most proven, widely used types which is also used for flu, polio and rabies jabs.

If the vaccine proves successful and receives regulatory approval following a rigorous assessment of available data, the Livingston facility will have the capacity to produce up to 250 million doses annually for shipment across the UK and around the world.

Scottish Secretary, Alister Jack said: “It’s incredibly exciting that a potential new COVID-19 vaccine will be manufactured right here in Scotland, at the Valneva plant in Livingston.

This big step forward is a testament to the talent and hard work of all the Valneva staff who have worked so far to get to this stage.

The UK government has invested millions into developing the Valneva vaccine, which is also supporting hundreds of highly skilled jobs in Scotland.

Chief Executive Officer of Valneva Thomas Lingelbach said: “We are extremely pleased to have achieved these 2 important milestones in such a short period of time. Our team in Scotland have done an amazing job to get manufacturing started so quickly.

“I would like to thank the UK Vaccines Taskforce and National Institute for Health Research who have played vital roles in the rapid recruitment and enrolment of the volunteers for the clinical study. We believe that our vaccine, assuming successful development, can make a major contribution in the UK and beyond.”

UK Health Secretary Matt Hancock said: “We’ve already secured 60 million doses of the Valneva vaccine which, if approved, will be another vital tool in our fight against this virus.​> The start of manufacturing in West Lothian today puts Scottish expertise right at the heart of the UK vaccine programme.

“Set to deliver millions more jabs across all four nations, this is yet another fantastic example of the strength of our Union, as we work together as one United Kingdom to tackle the virus.”

Interim Chair of the UK government’s Vaccines Taskforce Clive Dix said: “I am thrilled that manufacturing has begun in Livingston as a result of the excellent work being done by Valneva in conjunction with the Vaccines Taskforce.

“If approved this new vaccine will be a crucial part of our efforts to tackle coronavirus – not just in the UK but around the world.”

Lothian MSP, Miles Briggs, said: “This is excellent news that Valneva has started large-scale manufacturing of the Covid-19 vaccine, which the majority of us could be receiving.

“The Livingston site has the capacity to create hundreds of millions of vaccines that can be exported across the globe to help other countries in their fight to suppress Covid-19.

“UK government investment, doubling the workforce at the site, shows how Scotland is better prepared to overcome Covid-19 as part of the United Kingdom.”

Through the Vaccines Taskforce, the UK has secured early access to 367 million doses of seven of the most promising vaccines so far. To date, the UK government has invested over £230 million into manufacturing a successful vaccine.

The UK was the first country in the world to procure, authorise and then deploy both the Oxford/AstraZeneca and Pfizer/BioNTech vaccines.

Production of the Oxford University/AstraZeneca vaccine started last autumn where the bulk of the vaccine for the UK is being made in Oxfordshire and Staffordshire, with filling into vials taking place in North Wales.

In total, more than 7.1 million people across the UK have now had a least one dose of the vaccine.