Boosters provide high level of protection against death with Omicron

The latest data from the UK Health Security Agency (UKHSA) shows that boosters significantly reduce the risk of death with Omicron

The findings show that around 6 months after a second dose of any of the coronavirus (COVID-19) vaccines, protection against death with Omicron was around 60% in those aged 50 and over. However, this increased to around 95% 2 weeks after receiving a booster vaccine dose.

The data continue to show high levels of protection against hospitalisation from the booster. After a Pfizer booster (after either primary vaccination course), vaccine effectiveness against hospitalisation started at around 90%, dropping to around 75% after 10 to 14 weeks.

After a Moderna booster (mRNA-1273) (after either primary vaccination course), vaccine effectiveness against hospitalisation was 90% to 95% up to 9 weeks after vaccination. Longer follow-up data is not yet available and these figures may change with time.

An initial analysis of vaccine effectiveness against the Omicron variant sub-lineage known as BA.2 (designated VUI-22JAN-01 on 19 January), reveals a similar level of protection for symptomatic infection compared to Omicron (BA.1).

After 2 doses, effectiveness was 9% and 13% respectively for BA.1 and BA.2, after 25+ weeks. This increased to 63% for BA.1 and 70% for BA.2 from 2 weeks following a booster vaccine.

Dr Mary Ramsay, Head of Immunisation at UKHSA, said: “The evidence is clear – the vaccine helps to protect us all against the effects of COVID-19 and the booster is offering high levels of protection from hospitalisation and death in the most vulnerable members of our society.

“The pandemic is not over yet and the vaccine is the best way to increase your protection against the serious consequences of this virus – please book your appointment for your first, second or third vaccine without delay.”

Vaccines minister Maggie Throup said: “A booster vaccine is absolutely crucial to topping up your immunity against the Omicron variant.

“More than 80% of eligible adults in England have already received their booster and this has allowed us to ease COVID-19 restrictions.

“You can book online, visit a walk-in or one of our many pop-up vaccination clinics – please get boosted now.”