UK monkeypox case numbers begin to plateau

The UK Health Security Agency (UKHSA) has published the latest technical briefing, which shows early signs that the outbreak is plateauing.

As of 4 August, there are 2,859 confirmed and highly probable cases of monkeypox in the UK.

Analyses of the current UK outbreak shows that monkeypox continues to be transmitted primarily in interconnected sexual networks of gay, bisexual, or other men who have sex with men (GBMSM). The median age of confirmed cases in the UK was 37 years old. In England, 73% are known to be London residents over the course of the outbreak.

In the past few weeks, there have been a small number of women confirmed to have monkeypox but there is not enough evidence currently to suggest that there is sustained transmission outside of interconnected sexual networks. Twenty-two cases in women have been identified and 99% of all UK cases are male.

A small number of cases with no known travel history during their incubation period have been detected prior to 6 May, pre-dating the previous first-known report of a monkeypox case in the UK. This is not unexpected given our understanding of the outbreak to date.

Dr Meera Chand, Director of Clinical and Emerging Infections, UKHSA, said: “While the most recent data suggests the growth of the outbreak has slowed, we cannot be complacent. Be vigilant of and check yourself for monkeypox symptoms, including rashes and blisters.

“If you are concerned that you may have monkeypox symptoms, take a break from events, meeting with friends or having sexual contact. Instead, stay at home and contact 111 or your local sexual health service for advice.

The smallpox vaccine is being offered to individuals at higher risk of coming into contact with monkeypox in order to offer them protection and to reduce the spread of disease.”

The briefing now includes monkeypox genomic surveillance data from the UK. As is described globally, the majority of outbreak cases in the UK belong to a distinct genetic lineage (B.1) which has mutations of unknown significance when compared with the closest previously characterised monkeypox virus genomes.

UKHSA will continue to publish regular technical briefings as the response to the outbreak continues.

Monkeypox: First case in Scotland

Monkeypox has been confirmed in an individual in Scotland. The individual is receiving care and treatment appropriate to their condition and contact tracing is underway.

Monkeypox is a viral infection usually found in West and Central Africa. The West African strain that has been recently detected in the UK is generally a mild self-limiting illness, spread by very close contact with someone already infected and with symptoms of monkeypox. Most people recover within a few weeks.

Public Health Scotland (PHS) is working with the UK Health Security Agency (UKHSA), Public Health Wales and Northern Ireland HSC Health Protection Agency to monitor and respond to potential and confirmed cases of monkeypox in the UK.

As of Friday 20 May, the UKHSA has identified 20 cases in England but more are expected.

Dr Nick Phin, Director of Public Health Science and Medical Director, PHS explains: “Public Health Scotland is aware of an individual in Scotland who is confirmed to have monkeypox. The affected individual is being managed and treated in line with nationally agreed protocols and guidance.

“We have well established and robust infection control procedures for dealing with such cases of infectious disease and these will be strictly followed.

“We are working with NHS Boards and wider partners in Scotland and the UK to investigate the source of this infection. Close contacts of the case are being identified and provided with health information and advice. This may include the offer of vaccination.

“The overall risk to the general public is low.

“Anyone with an unusual blister-like rash or small number of blister-like sores on any part of their body, including their genital area, should avoid close contact with others and seek medical advice if they have any concerns.”

Symptoms

Initial symptoms of monkey pox include fever or high temperature, headache, muscle aches, backache, swollen lymph nodes, chills and exhaustion.

A blister-like rash or small number of blister-like sores can develop, often beginning on the face, then spreading to other parts of the body, including the genital area.

The rash changes and goes through different stages, before finally forming a scab, which typically falls off over the course of a couple of weeks. Individuals are infectious from the point symptoms start until all the scabs fall off. During this time close contact with others must be avoided.

UKHSA identifies thirty-six more cases of monkeypox in England

The UK Health Security Agency (UKHSA) has detected 36 additional cases of monkeypox in England.

The latest cases bring the total number of monkeypox cases confirmed in England since 7 May to 56.

The virus does not usually spread easily between people, but it can be passed on through close person-to-person contact or contact with items used by a person who has monkeypox, such as clothes, bedding or utensils. Monkeypox is usually a self-limiting illness and most people recover within a few weeks.

While the current outbreak is significant and concerning, the risk to the UK population remains low.

Anyone with unusual rashes or lesions on any part of their body, especially their genitalia, should immediately contact NHS 111 or their local sexual health service.

A notable proportion of cases detected have been in gay and bisexual men, so UKHSA continues to urge this community to be alert to monkeypox symptoms.

People should notify clinics ahead of their visit and can be assured their call or discussion will be treated sensitively and confidentially.

Dr Susan Hopkins, Chief Medical Adviser, UKHSA, said: Alongside reports of further cases being identified in other countries globally, we continue to identify additional cases in the UK. Thank you to everyone who has come forward for testing already and supported our contact tracing efforts – you are helping us limit the spread of this infection in the UK.

“Because the virus spreads through close contact, we are urging everyone to be aware of any unusual rashes or lesions and to contact a sexual health service if they have any symptoms.

“A notable proportion of recent cases in the UK and Europe have been found in gay and bisexual men so we are particularly encouraging these men to be alert to the symptoms.”

UKHSA health protection teams are contacting people considered to be high-risk contacts of confirmed cases and are advising those who have been risk assessed and remain well to isolate at home for up to 21 days.

In addition, UKHSA has purchased supplies of a safe smallpox vaccine (called Imvanex) and this is being offered to identified close contacts of someone diagnosed with monkeypox to reduce the risk of symptomatic infection and severe illness.

We continue to engage with partners across the sector to ensure people are aware of the signs and symptoms and what action to take.

The vaccination of high-risk contacts of cases is underway. As of 10am on 23 May 2022, over 1,000 doses of Imvanex have been issued, or are in the process of being issued, to NHS Trusts. There remain over 3,500 doses of Imvanex in the UK.