NHS Lothian to play key role in COVID-19 vaccine trial

NHS Lothian is set to become involved in a major clinical vaccine trial testing the new Covid-19 vaccine in collaboration with Oxford University and 17 other sites across the UK.

The vaccine study will run at both the Western General Hospital and the Royal Infirmary of Edinburgh.

The aim is to enrol approximately 600 Lothian frontline health and social care workers which will include doctors, nurses, emergency department staff, paramedics, care home nurses, porters and domestics to test a new vaccine.

Screening volunteer health and social care workers is planned to begin from next week.

Dr Tracey Gillies, Medical Director, NHS Lothian, said: “We are pleased to be participating in this unprecedented clinical vaccine trial and I would like to thank everyone for their participation in this vital research.

“Their involvement will be essential in the development of a vaccine and this pioneering and important research allows us the opportunity to contribute to the development of a globally approved vaccine against Covid-19.”

The main focus of the study will be to develop a safe vaccine for use across the population.

As part of that, it will investigate the effectiveness of the vaccine, to pinpoint any side effects and to establish if it induces good immune responses against the virus.

To recruit the large number of participants needed for this trial, multiple clinical research sites across the UK are involved in delivering the study. The collaborative effort, led by the University of Oxford, will see vaccinations taking place throughout May and June.

Health Secretary Jeane Freeman said: “I am delighted that the Universities of Edinburgh and Glasgow along with NHS colleagues are taking part in the human safety trials for the development of a COVID-19 vaccine by Oxford University.

“Scotland has a long established reputation for medical research, and I would like to thank the research community across the country. The pace of work and the commitment of teams across Scotland has been outstanding and is testament to the world-class research infrastructure and expertise we have here.

“Of course, while the prospect of an effective vaccine developed here in the UK is exciting, there is no guarantee of success and we must continue to follow the guidelines set out by the Scottish Government to reduce the spread of COVID-19 and protect our NHS.”

New research into Type 1 Diabetes

NHS Lothian’s diabetes research teams based at the Western General Hospital (WGH) and the Royal Infirmary of Edinburgh (RIE) have launched a number of exciting new trials to help us understand what might cause type 1 diabetes and how to prevent it.

These new studies include INNODIA, a Europe wide study recruiting people with newly diagnosed type 1 diabetes and unaffected family members. As diabetes affects 1 in 18 people in Scotland, with around 5,000 people with type 1 and 37,000 with type 2 diabetes in the NHS Lothian region, research to improve patient care and develop new treatments is vitally important.

Key to the success of the research are the volunteers who take part in studies. An easy way for people to participate is to join the NHS Research Scotland Diabetes research register.

Alison Sudworth, Diabetes Specialist Research Nurse in the RIE, said: “Getting more people involved in diabetes research will help make inroads into understanding the disease and create new treatments. For instance, one part of our GoDarts study is looking at genetics.”

Diabetes can damage the heart, blood vessels, nerves, eyes and kidneys and the WGH team have two trials that aim to improve the health of patients with complications.

Lesley Steven, Specialist Research Nurse at WGH said: “Recruitment in clinical trials is often challenging, particularly in diabetes renal studies. Renal patients often have limited treatment options, so trials in this area are vital to allow access to new drugs that would otherwise not be available to them.”

For more information contact: WGH 0131 537 3327 or RIE 0131 242 1456. 

Any diabetes research project can make use of the NHS Research Scotland Diabetes research register, contact administrator-sdrn@dundee.ac.uk or phone 01382 383595 for more information.