JCVI advises use of additional bivalent vaccine for autumn booster campaign

Following on from the previous advice on which vaccines should be used in this year’s autumn booster programme, the Joint Committee on Vaccination and Immunisation (JCVI) has updated its published advice to include an additional bivalent vaccine now approved by the Medicines and Healthcare products Regulatory Agency (MHRA).

Studies indicate the Pfizer-BioNTech bivalent vaccine produces a marginally higher immune response against some variants than the Pfizer-BioNTech mRNA Original ‘wild-type’ vaccine. The clinical relevance of these small differences is uncertain.

‘Bivalent’ vaccines have been developed by global manufacturers since the emergence and dominance of the Omicron variant. These vaccines are targeted against antigens (substances that induce an immune response) from 2 different COVID-19 strains, or variants.

All of the available booster vaccines offer very good protection against severe illness from COVID-19. As more vaccines continue to be developed, the committee will consider their use in the autumn programme.

Professor Wei Shen Lim, Chair of COVID-19 immunisation on the JCVI, said: “It is very encouraging that more vaccines continue to become available and we now have another option to add to the vaccines already advised for the autumn booster campaign.

“Winter is typically the time of greatest threat from respiratory infections. We strongly encourage everyone who is eligible to have their booster vaccine this autumn when it is offered. This is our best defence against becoming severely ill from COVID-19.”

Pfizer/BioNTech bivalent COVID-19 booster approved by UK medicines regulator

A second, “bivalent” vaccine was yesterday approved as a booster by the Medicines and Healthcare products Regulatory Agency (MHRA) after it was found to meet the UK regulator’s standards of safety, quality and effectiveness.

The updated booster vaccine made by Pfizer/BioNTech, targeting two coronavirus variants, has been approved for use in individuals aged 12 years and above. This decision has been endorsed by the Commission on Human Medicines, after a careful review of the evidence.

In each dose of the booster vaccine, ‘Comirnaty bivalent Original/Omicron’, half of the vaccine (15 micrograms) targets the original virus strain and the other half (15 micrograms) targets Omicron (BA.1).

The MHRA’s decision is based on data from a clinical trial which showed that a booster dose with the bivalent Pfizer/BioNTech vaccine triggers a strong immune response against both Omicron and the original strain. Safety monitoring showed that the side effects observed were the same as those seen for the original Pfizer/BioNTech booster dose and were typically mild and self-resolving, and no new serious safety concerns were identified.

Dr June Raine, MHRA Chief Executive said: I am pleased to announce that we now have a second approved vaccine for the UK Autumn booster programme. The clinical trial of the Pfizer/BioNTech bivalent vaccine showed a strong immune response against the Omicron BA.1 variant as well as the original strain.

“Bivalent vaccines are helping us to meet the challenge of an ever-evolving virus, to help protect people against COVID-19 variants.

“We have in place a comprehensive safety surveillance strategy for all UK-approved COVID-19 vaccines, and this will include the updated booster we approved today.”

Professor Sir Munir Pirmohamed, Chair of the Commission on Human Medicines said: “Following an independent review of the safety, quality and effectiveness of the vaccine, the Commission on Human Medicines and its COVID-19 Vaccines Expert Working Group supports the MHRA’s decision.

“As with any medicinal product, including vaccines, it is important to continually monitor effectiveness and safety when it is deployed, and we have the relevant processes and expertise in this country to do that.

“The Joint Committee on Vaccination and Immunisation (JCVI) will advise on how this vaccine should be offered as part of the deployment programme.”

NHS Lothian encourages parents to get children vaccinated against flu 

NHS Lothian is encouraging parents and carers to help keep children healthy over the school terms this winter by getting them vaccinated against flu. All primary and secondary school pupils are eligible for the vaccine, which is given in schools as a painless nasal spray.

Getting children vaccinated against flu reduces the chances of them missing class time and other activities due to illness and helps prevent them passing the illness to vulnerable family members.

Consent packs containing a letter, leaflet and consent form will be sent home to parents and carers of school children on return to school in August. Secondary pupils can self-consent, though they are encouraged to speak to a parent or carer first.

Letters with appointment details for children aged two to five years who are not yet at school will begin to arrive at homes from September.

Parents and carers should call the number on their child’s letter if their child has missed their appointment or needs to reschedule.

The nasal spray is a quick and painless way of delivering the flu vaccine to children and should start to provide protection within 10-14 days.

Pat Wynne, Nurse Director for NHS Lothian who is overseeing this year’s programme, said: “Getting the nasal spray flu vaccine is the best way to protect your child and those around them. The flu virus changes over time so your child needs to get the vaccine each year to help stay protected.

“Please look out for your child’s consent pack, which they will receive through school from August, and ensure that their completed consent form is returned on time if you wish them to receive the vaccine.”

Public Health Minister Maree Todd said: “Schools are back but we want to keep flu out, which is why all primary and secondary school children are being offered the free flu vaccine.

“Flu can be serious, even for healthy children, so the vaccine offers the best possible protection for your child and those around them who may be more vulnerable to flu. Getting your child vaccinated can help prevent them getting sick, from spreading flu, and requiring time off school and away from other activities.”

School children will receive the flu vaccine in school between September and December. Parents of two to five-year-olds who are not yet at school will be given information about where their child will be vaccinated in their appointment letter. In a small number of cases, the nasal spray may not be suitable, and the vaccine can be given as an injection in the arm instead.

For more information about the flu vaccine, visit NHS Inform or call 0800 030 8013.

Winter Vaccines

Scotland’s Winter Vaccine Programme will see eligible groups invited forward for vaccination against flu and/or COVID-19.

Following advice from the Joint Committee on Vaccination and Immunisation (JCVI), the following groups will be offered both the flu and COVID-19 vaccines this year:

• aged 50 or over
• residents and staff working in a care home for older adults
• younger adults in long stay nursing and residential care settings
• frontline health and social care workers
• Those aged 5 to 49 years with an eligible health condition, including those with poorly controlled asthma
• Those aged 5 to 49 years who are:
– a household contact of someone with a weakened immune system
– an unpaid carer or a young carer (16 years or over)
– pregnant

The flu vaccine is also recommended for:

• people aged 16 to 49 years with an eligible health condition, including well controlled asthma
• children aged 6 months to 2 years with an eligible health condition
• all children aged 2 to 5 years (not yet at school)
• all primary and secondary school pupils
• nursery, primary and secondary school teachers and pupil-facing support workers in local authority and independent settings
• prison population and prison officers and support workers who deliver direct front-facing detention services.

Appointments for priority groups will be made available as the programme progresses – people in those groups should wait until they are contacted or called forward. Read the latest update from the Scottish Government here.

UKHSA calls for everyone to get their flu jab this week

The UK Health Security Agency (UKHSA) is urging all those eligible to take up their flu vaccine by 10 December to ensure protection in time for Christmas.

The vaccine takes 14 days before it provides maximum protection, so people should get it before 10 December to help keep themselves and vulnerable relatives safe throughout the festive season.

Flu is a highly infectious disease and can lead to serious complications for those living with a long-term health condition, including respiratory and heart conditions, diabetes, kidney disease, liver disease or a chronic neurological disease like multiple sclerosis or cerebral palsy. People with underlying health conditions overall are 11 times more likely to die if they catch flu compared to healthy adults.

Pregnant women are also at increased risk of serious complications and should have the flu vaccine to help protect themselves and their babies.

While many people aged 65 and over have already come forward for their flu vaccination, exceeding the WHO target of 75%, less than half of those with underlying health conditions have taken up the offer. Uptake in pregnant women also lags behind other groups, with just 34.4% vaccinated so far this season.

While levels of flu infection are still low, typically levels ramp up over December, with a peak in January. We are calling on people to take up the flu vaccine, along with practicing good hygiene, ventilating rooms, and staying at home if unwell.

Health and Social Care Secretary, Sajid Javid said: “Getting your winter vaccines – whether that is your flu jab if eligible or your booster jab –  is one of the most important things people can do for yourself an your family this winter.

“Record numbers of people took up the offer of a free flu vaccine last year and the programme is expanding even further this year, with a record 35 million people in England eligible.

“Don’t delay – book your flu vaccine as soon as possible.”

Dr Conall Watson, Consultant Epidemiologist at UKHSA, said: “The threat of flu has not gone away – it can cause serious illness and be fatal.

“Flu vaccination saves lives. If you are eligible, you don’t have to wait to be called up – book your flu vaccine as soon as possible to help protect yourself and family this Christmas.”

Almost 20 million COVID-19 booster vaccines and third doses have been administered in the UK.

NHS Lothian warns of children flu vaccination letter mistake

Are you a parent or guardian of a 2-5 year old in Edinburgh, East Lothian or Midlothian? Check out this important update regarding flu vaccine appointments 👇

More information on the children’s flu vaccine is available here:

– https://www.nhsinform.scot/…/children-aged-2-5-years

Councillor George Gordon calls on citizens to get their flu vaccination

In the first week of the winter vaccination programme, 27,000 people have come forward to get their flu vaccine, which is a great response ((writes Edinburgh Integration Joint Board member and Forth Councillor GEORGE GORDON).

We’ve all seen the devastating effect the pandemic has had in the past 18 months so it’s really important we all play our part to limit the impact this winter.  

This is a personal appeal to encourage everyone who’s eligible to get their flu vaccination this winter. COVID-19 has not gone away so it’s more important than ever to protect yourself by getting the vaccination and do your bit to ease the pressure on social care, GP surgeries and hospitals over winter. 

Many of you will already have received a letter either with an appointment or asking you to book one online. I know there’s been an issue with the scheduling of some flu appointments via the national booking system.

This means some people’s appointments are not as local as would have been expected, and a few cases where people who are housebound have been asked to go to an appointment. I know how concerning this is for people who cannot travel. 

If you have received a letter with an appointment that you are unable to attend, you can rearrange your appointment for a more local venue by going online at nhsinform.scot/flu-vaccine/invitations-and-appointments/rearrange-your-flu-vaccine-appointmen or ring the national flu vaccination helpline on 0800 030 8013 for help to re-book.

More local appointments are now available for people who find it difficult to travel. If you are housebound and normally get your flu jab at home then you will get it at home again this year, even if you’ve received an appointment letter.

It’s really good to see that so many people have been turning out to get their vaccinations. The Royal Highland Centre site experienced a slight delay in topping up vaccination stocks on Tuesday morning (5 October) due to the level of demand across other sites and some people were asked to return the following day.

This was resolved within an hour and I can assure you that we have good vaccine stocks in Edinburgh. 

Across Scotland, GP surgeries are no longer responsible for flu vaccinations for their patients. Now, health and social care partnerships manage the flu programme. In Edinburgh we have a range of drive through and walk through clinics for adults which will open at weekends during October and November.

Edinburgh’s main site is in Lowland Hall at the Royal Highland Centre which is open seven days a week and easy to access by public transport (buses 100, 200 and 400). We also have small local clinics for people who can’t make their way to Ingliston.

Children have received a letter for their parents or carers about their vaccine. If it’s been six months since your second dose of the COVID vaccine, you may also get your COVID vaccine booster at the same time as your flu vaccine. 

It’s a massive programme and this year there’s more people than ever eligible to get a vaccine which is great news. You can now get the vaccine if you’re over 50, pregnant, an unpaid carer, at risk because of an existing health condition, or because of the job that you do. You can check if you are eligible for a flu vaccine, or find more information, at nhsinform.scot/flu.

I’d really encourage you to take up that offer – go to your vaccination appointment if you have been given one or book an appointment on the online portal if you’ve been asked to do that. 

Please don’t be in any doubt – flu is serious. Getting the vaccine will protect you, your family and friends, and also our vital NHS and social care services.

Over sixties invited for vaccine

Second phase of flu vaccine begins today

People aged 60 – 64 will be invited to receive the seasonal flu vaccine from 1 December as part of the largest flu immunisation program ever delivered in Scotland.

The most effective way to protect against flu this winter is continuing to prioritise those who are most at risk, especially in light of the coronavirus (COVID-19) pandemic.

With vaccination for the first phase of the flu programme well under way, eligibility is being extended next to those aged 60-64.

Those entitled to the flu vaccine will receive an invitation letter by post from their health board letting them know where they can receive the vaccine and how to book an appointment.

Deputy Chief Medical Officer Dr Nicola Steedman said: “Flu is serious in itself, but with COVID-19 also circulating in the community, getting a flu jab is more important than ever.

“For those who may be concerned about going to get the flu vaccine, we can assure you that there will be strict infection and prevention control measures in place at delivery sites to protect you.

“The vaccine is safe, and the best protection we have against flu. This year more than ever it is important that those invited for vaccination take up the offer to protect themselves, their family and, where possible, the NHS. I’ve had my vaccine already, and would urge all of those who are eligible, including the new group of 60-64 year olds, to get one too.

“We will continue to adapt our approach to any changes that occur throughout flu season, always prioritising those most at risk from flu, as well as seeking to protect the NHS.”

NHS Inform is the best source of information for finding out more about how you will be invited to book a flu vaccine appointment 

Flu vaccine: who gets it?

Flu immunisation begins in autumn. This year, with coronavirus (COVID-19) circulating, the flu vaccine is being offered to more people than ever before in Scotland.

Please note that flu vaccinations are being offered differently in some areas of Scotland this year, and might not be at your GP practice as in previous years.

The following groups are eligible for the free flu vaccine this year:

A second phase is planned to begin in December, and will include those aged 55 to 64 (by 31 March 2021) who would not usually be eligible.

The vaccine is safe, effective and is the best protection against flu. It reduces your risk of getting flu and spreading it to others, especially those who are most at risk. 

You have to be immunised every year because the virus changes each year and your immunity reduces over time.  The vaccine takes around ten days to work so the sooner you get it the better.  Help our NHS avoid the pressure that a spike in seasonal flu would put on top of coronavirus.

Getting your flu vaccine is one of the most important reasons for leaving your home. Strict infection prevention and control measures will be in place during vaccination.

If you are eligible due to a health condition, the risk of getting seriously ill with the flu virus is greater than the risk of going to get your vaccine.

Find out if you’re eligible for a free flu vaccine and get more information about this year’s vaccine. Or call 0800 22 44 88 (open 8 am – 10 pm, 7 days a week).